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Establishment of a Novel Oral Murine Model of Ricin Intoxication and Efficacy Assessment of Ovine Ricin Antitoxins

Ricin, produced from the castor beans of Ricinus communis, is a cytotoxin that exerts its action by inactivating ribosomes and causing cell death. Accidental (e.g., ingestion of castor beans) and/or intentional (e.g., suicide) exposure to ricin through the oral route is an area of concern from a pub...

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Detalles Bibliográficos
Autores principales: Whitfield, Sarah J., Padgen, Debbie B., Knight, Simon, Gwyther, Robert J., Holley, Jane L., Clark, Graeme C., Green, A. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764460/
https://www.ncbi.nlm.nih.gov/pubmed/33302573
http://dx.doi.org/10.3390/toxins12120784