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Establishment of a Novel Oral Murine Model of Ricin Intoxication and Efficacy Assessment of Ovine Ricin Antitoxins
Ricin, produced from the castor beans of Ricinus communis, is a cytotoxin that exerts its action by inactivating ribosomes and causing cell death. Accidental (e.g., ingestion of castor beans) and/or intentional (e.g., suicide) exposure to ricin through the oral route is an area of concern from a pub...
Autores principales: | Whitfield, Sarah J., Padgen, Debbie B., Knight, Simon, Gwyther, Robert J., Holley, Jane L., Clark, Graeme C., Green, A. Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764460/ https://www.ncbi.nlm.nih.gov/pubmed/33302573 http://dx.doi.org/10.3390/toxins12120784 |
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