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Data-driven prioritization and preclinical evaluation of therapeutic targets in glioblastoma

BACKGROUND: Patients with glioblastoma (GBM) have a dismal prognosis, and there is an unmet need for new therapeutic options. This study aims to identify new therapeutic targets in GBM. METHODS: mRNA expression data of patient-derived GBM (n = 1279) and normal brain tissue (n = 46) samples were coll...

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Detalles Bibliográficos
Autores principales:	Brahm, Cyrillo G, Abdul, U Kulsoom, Houweling, Megan, van Linde, Myra E, Lagerweij, Tonny, Verheul, Henk M W, Westerman, Bart A, Walenkamp, Annemiek M E, Fehrmann, Rudolf S N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764503/ https://www.ncbi.nlm.nih.gov/pubmed/33392504 http://dx.doi.org/10.1093/noajnl/vdaa151

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