Cargando…

Reactive Oxygen Species-Mediated Autophagy by Ursolic Acid Inhibits Growth and Metastasis of Esophageal Cancer Cells

Ursolic acid (UA) possesses various pharmacological activities, such as antitumorigenic and anti-inflammatory effects. In the present study, we investigated the mechanisms underlying the effects of UA against esophageal squamous cell carcinoma (ESCC) (TE-8 cells and TE-12 cells). The cell viability...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Na-Ri, Meng, Ruo Yu, Rah, So-Young, Jin, Hua, Ray, Navin, Kim, Seong-Hun, Park, Byung Hyun, Kim, Soo Mi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764507/ https://www.ncbi.nlm.nih.gov/pubmed/33321911 http://dx.doi.org/10.3390/ijms21249409

Ejemplares similares

Activating Hippo Pathway via Rassf1 by Ursolic Acid Suppresses the Tumorigenesis of Gastric Cancer
por: Kim, Seong-Hun, et al.
Publicado: (2019)

Ursolic Acid Accelerates Paclitaxel-Induced Cell Death in Esophageal Cancer Cells by Suppressing Akt/FOXM1 Signaling Cascade
por: Meng, Ruo Yu, et al.
Publicado: (2021)

Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis
por: Meng, Ruo Yu, et al.
Publicado: (2023)

Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin is mediated by targeting the Akt signaling pathway and activating the Hippo signaling pathway
por: Hu, Dan, et al.
Publicado: (2022)

Herp regulates intracellular survival of Mycobacterium tuberculosis H37Ra in macrophages by regulating reactive oxygen species-mediated autophagy
por: Son, Sang-Hun, et al.
Publicado: (2023)

Inactivation of the Akt/FOXM1 Signaling Pathway by Panobinostat Suppresses the Proliferation and Metastasis of Gastric Cancer Cells
por: Lee, Na-Ri, et al.
Publicado: (2021)

Ursolic acid in health and disease
por: Seo, Dae Yun, et al.
Publicado: (2018)

Autophagy inhibition enhances the inhibitory effects of ursolic acid on lung cancer cells
por: Wang, Min, et al.
Publicado: (2020)

RhBMP-2 Activates Hippo Signaling through RASSF1 in Esophageal Cancer Cells
por: Kim, Soo Mi, et al.
Publicado: (2016)

ATM at the crossroads of reactive oxygen species and autophagy
por: Xie, Xiaochen, et al.
Publicado: (2021)

Ethoxycarbonylmethyl ursolate
por: Yang, Wei, et al.
Publicado: (2008)

Enhancement of Platelet Aggregation by Ursolic Acid and Oleanolic Acid
por: Kim, Mikyung, et al.
Publicado: (2014)

Induction of Autophagy by Ursolic Acid Promotes the Elimination of Trypanosoma cruzi Amastigotes From Macrophages and Cardiac Cells
por: Vanrell, María Cristina, et al.
Publicado: (2022)

The Interrelation between Reactive Oxygen Species and Autophagy in Neurological Disorders
por: Fang, Congcong, et al.
Publicado: (2017)

The Role of Reactive Oxygen Species and Autophagy in Periodontitis and Their Potential Linkage
por: Liu, Chengcheng, et al.
Publicado: (2017)

Carboxymethyl ursolate monohydrate
por: Zhong, Yan, et al.
Publicado: (2011)

Recent studies on ursolic acid and its biological and pharmacological activity
por: Lee, Sook Young, et al.
Publicado: (2016)

Ursolic Acid Enhances the Sensitivity of MCF-7 and MDA-MB-231 Cells to Epirubicin by Modulating the Autophagy Pathway
por: Wang, Zhennan, et al.
Publicado: (2022)

Expression of Autophagy and Reactive Oxygen Species-Related Proteins in Lacrimal Gland Adenoid Cystic Carcinoma
por: Koo, Ja Seung, et al.
Publicado: (2016)

Current research progress in the role of reactive oxygen species in esophageal adenocarcinoma
por: Hu, Youzhen, et al.
Publicado: (2021)

The role of reactive oxygen species and autophagy in safingol-induced cell death
por: Ling, L-U, et al.
Publicado: (2011)

Molecular Interactions Between Reactive Oxygen Species and Autophagy in Kidney Disease
por: Kaushal, Gur P., et al.
Publicado: (2019)

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
por: Su, Lian-Jiu, et al.
Publicado: (2019)

Reactive Oxygen Species as a Link between Antioxidant Pathways and Autophagy
por: Li, Dan, et al.
Publicado: (2021)

Autophagy Ameliorates Reactive Oxygen Species-Induced Platelet Storage Lesions
por: Zhao, Xi, et al.
Publicado: (2022)

HSP27 Protects Skin From Ultraviolet B -Induced Photodamage by Regulating Autophagy and Reactive Oxygen Species Production
por: Wang, Zi-Yue, et al.
Publicado: (2022)

PERK activation by SB202190 ameliorates amyloidogenesis via the TFEB-induced autophagy-lysosomal pathway
por: Do, Mihyang, et al.
Publicado: (2022)

NAADP-mediated Ca(2+) signaling promotes autophagy and protects against LPS-induced liver injury
por: Rah, So-Young, et al.
Publicado: (2017)

Berberine protects against esophageal mucosal damage in reflux esophagitis by suppressing proinflammatory cytokines
por: CHOO, BYUNG KIL, et al.
Publicado: (2013)

JI017 Induces Cell Autophagy and Apoptosis via Elevated Levels of Reactive Oxygen Species in Human Lung Cancer Cells
por: Ku, Jin Mo, et al.
Publicado: (2023)

Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells
por: Lewinska, Anna, et al.
Publicado: (2017)

Antimicrobial Activity of Oleanolic and Ursolic Acids: An Update
por: Jesus, Jéssica A., et al.
Publicado: (2015)

Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives
por: do Nascimento, Patrícia G.G., et al.
Publicado: (2014)

Ursolic Acid and Its Derivatives as Bioactive Agents
por: Mlala, Sithenkosi, et al.
Publicado: (2019)

Antagonistic effect of ursolic acid on Staphylococcal biofilms
por: Jyothi, J. Shiva, et al.
Publicado: (2018)

Ursolic Acid Analogs as Potential Therapeutics for Cancer
por: Panda, Siva S., et al.
Publicado: (2022)

C-Peptide Prevents Hyperglycemia-Induced Endothelial Apoptosis Through Inhibition of Reactive Oxygen Species–Mediated Transglutaminase 2 Activation
por: Bhatt, Mahendra Prasad, et al.
Publicado: (2013)

Ursolic Acid-Induced Elevation of Serum Irisin Augments Muscle Strength During Resistance Training in Men
por: Bang, Hyun Seok, et al.
Publicado: (2014)

Not Alternative, But Additional Use of Extracorporeal Membrane Oxygenation in Patients with Life-Threatening Pulmonary Thromboembolism
por: Kim, So Ree, et al.
Publicado: (2020)

Antitumor Effects of Natural Bioactive Ursolic Acid in Embryonic Cancer Stem Cells
por: Kang, Dong Young, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nda7m749hgt1odqdeqmgolscna