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Review on the Impact of Polyols on the Properties of Bio-Based Polyesters

Bio-based polyol polyesters are biodegradable elastomers having potential utility in soft tissue engineering. This class of polymers can serve a wide range of biomedical applications. Materials based on these polymers are inherently susceptible to degradation during the period of implantation. Facto...

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Detalles Bibliográficos
Autores principales: Lang, Kening, Sánchez-Leija, Regina J., Gross, Richard A., Linhardt, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764582/
https://www.ncbi.nlm.nih.gov/pubmed/33322728
http://dx.doi.org/10.3390/polym12122969
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author Lang, Kening
Sánchez-Leija, Regina J.
Gross, Richard A.
Linhardt, Robert J.
author_facet Lang, Kening
Sánchez-Leija, Regina J.
Gross, Richard A.
Linhardt, Robert J.
author_sort Lang, Kening
collection PubMed
description Bio-based polyol polyesters are biodegradable elastomers having potential utility in soft tissue engineering. This class of polymers can serve a wide range of biomedical applications. Materials based on these polymers are inherently susceptible to degradation during the period of implantation. Factors that influence the physicochemical properties of polyol polyesters might be useful in achieving a balance between durability and biodegradability. The characterization of these polyol polyesters, together with recent comparative studies involving creative synthesis, mechanical testing, and degradation, have revealed many of their molecular-level differences. The impact of the polyol component on the properties of these bio-based polyesters and the optimal reaction conditions for their synthesis are only now beginning to be resolved. This review describes our current understanding of polyol polyester structural properties as well as a discussion of the more commonly used polyol monomers.
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spelling pubmed-77645822020-12-27 Review on the Impact of Polyols on the Properties of Bio-Based Polyesters Lang, Kening Sánchez-Leija, Regina J. Gross, Richard A. Linhardt, Robert J. Polymers (Basel) Review Bio-based polyol polyesters are biodegradable elastomers having potential utility in soft tissue engineering. This class of polymers can serve a wide range of biomedical applications. Materials based on these polymers are inherently susceptible to degradation during the period of implantation. Factors that influence the physicochemical properties of polyol polyesters might be useful in achieving a balance between durability and biodegradability. The characterization of these polyol polyesters, together with recent comparative studies involving creative synthesis, mechanical testing, and degradation, have revealed many of their molecular-level differences. The impact of the polyol component on the properties of these bio-based polyesters and the optimal reaction conditions for their synthesis are only now beginning to be resolved. This review describes our current understanding of polyol polyester structural properties as well as a discussion of the more commonly used polyol monomers. MDPI 2020-12-12 /pmc/articles/PMC7764582/ /pubmed/33322728 http://dx.doi.org/10.3390/polym12122969 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lang, Kening
Sánchez-Leija, Regina J.
Gross, Richard A.
Linhardt, Robert J.
Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title_full Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title_fullStr Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title_full_unstemmed Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title_short Review on the Impact of Polyols on the Properties of Bio-Based Polyesters
title_sort review on the impact of polyols on the properties of bio-based polyesters
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764582/
https://www.ncbi.nlm.nih.gov/pubmed/33322728
http://dx.doi.org/10.3390/polym12122969
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