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Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent

Titanium and its alloys belong to the group of materials used in implantology due to their biocompatibility, outstanding corrosion resistance and good mechanical properties. However, the value of Young’s modulus is too high in comparison with the human bone, which could result in the failure of impl...

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Autores principales: Školáková, Andrea, Körberová, Jana, Málek, Jaroslav, Rohanová, Dana, Jablonská, Eva, Pinc, Jan, Salvetr, Pavel, Gregorová, Eva, Novák, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764597/
https://www.ncbi.nlm.nih.gov/pubmed/33316967
http://dx.doi.org/10.3390/ma13245607
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author Školáková, Andrea
Körberová, Jana
Málek, Jaroslav
Rohanová, Dana
Jablonská, Eva
Pinc, Jan
Salvetr, Pavel
Gregorová, Eva
Novák, Pavel
author_facet Školáková, Andrea
Körberová, Jana
Málek, Jaroslav
Rohanová, Dana
Jablonská, Eva
Pinc, Jan
Salvetr, Pavel
Gregorová, Eva
Novák, Pavel
author_sort Školáková, Andrea
collection PubMed
description Titanium and its alloys belong to the group of materials used in implantology due to their biocompatibility, outstanding corrosion resistance and good mechanical properties. However, the value of Young’s modulus is too high in comparison with the human bone, which could result in the failure of implants. This problem can be overcome by creating pores in the materials, which, moreover, improves the osseointegration. Therefore, TiSi2 and TiSi2 with 20 wt.% of the pore-forming agent (PA) were prepared by reactive sintering and compared with pure titanium and titanium with the addition of various PA content in this study. For manufacturing implants (especially augmentation or spinal replacements), titanium with PA seemed to be more suitable than TiSi2 + 20 wt.% PA. In addition, titanium with 30 or 40 wt.% PA contained pores with a size allowing bone tissue ingrowth. Furthermore, Ti + 30 wt.% PA was more suitable material in terms of corrosion resistance; however, its Young’s modulus was higher than that of the human bone while Ti + 40 wt.% PA had a Young’s modulus close to the human bone.
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spelling pubmed-77645972020-12-27 Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent Školáková, Andrea Körberová, Jana Málek, Jaroslav Rohanová, Dana Jablonská, Eva Pinc, Jan Salvetr, Pavel Gregorová, Eva Novák, Pavel Materials (Basel) Article Titanium and its alloys belong to the group of materials used in implantology due to their biocompatibility, outstanding corrosion resistance and good mechanical properties. However, the value of Young’s modulus is too high in comparison with the human bone, which could result in the failure of implants. This problem can be overcome by creating pores in the materials, which, moreover, improves the osseointegration. Therefore, TiSi2 and TiSi2 with 20 wt.% of the pore-forming agent (PA) were prepared by reactive sintering and compared with pure titanium and titanium with the addition of various PA content in this study. For manufacturing implants (especially augmentation or spinal replacements), titanium with PA seemed to be more suitable than TiSi2 + 20 wt.% PA. In addition, titanium with 30 or 40 wt.% PA contained pores with a size allowing bone tissue ingrowth. Furthermore, Ti + 30 wt.% PA was more suitable material in terms of corrosion resistance; however, its Young’s modulus was higher than that of the human bone while Ti + 40 wt.% PA had a Young’s modulus close to the human bone. MDPI 2020-12-09 /pmc/articles/PMC7764597/ /pubmed/33316967 http://dx.doi.org/10.3390/ma13245607 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Školáková, Andrea
Körberová, Jana
Málek, Jaroslav
Rohanová, Dana
Jablonská, Eva
Pinc, Jan
Salvetr, Pavel
Gregorová, Eva
Novák, Pavel
Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title_full Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title_fullStr Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title_full_unstemmed Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title_short Microstructural, Mechanical, Corrosion and Cytotoxicity Characterization of Porous Ti-Si Alloys with Pore-Forming Agent
title_sort microstructural, mechanical, corrosion and cytotoxicity characterization of porous ti-si alloys with pore-forming agent
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764597/
https://www.ncbi.nlm.nih.gov/pubmed/33316967
http://dx.doi.org/10.3390/ma13245607
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