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The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model
(1) Background: Chronic venous insufficiency (CVI) is a common disorder related to functional and morphological abnormalities of the venous system. Inflammatory processes and angiogenesis alterations greatly concur to the onset of varicose vein. KYP-2047 is a selective inhibitor of prolyl oligopepti...
Autores principales: | Casili, Giovanna, Lanza, Marika, Scuderi, Sarah Adriana, Messina, Salvatore, Paterniti, Irene, Campolo, Michela, Esposito, Emanuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764674/ https://www.ncbi.nlm.nih.gov/pubmed/33322134 http://dx.doi.org/10.3390/biomedicines8120604 |
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