Cargando…

NOTCH1 Signaling in Head and Neck Squamous Cell Carcinoma

Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma (HNSCC), which is common and lethal. Efforts to develop such therapies are hindered by a genomic landscape dominated by the loss of tumor suppressor function, including NOTCH1 that is frequently mutated in HNSC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shah, Pooja A., Huang, Chenfei, Li, Qiuli, Kazi, Sawad A., Byers, Lauren A., Wang, Jing, Johnson, Faye M., Frederick, Mitchell J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764697/ https://www.ncbi.nlm.nih.gov/pubmed/33322834 http://dx.doi.org/10.3390/cells9122677

Ejemplares similares

High expression of oxidative phosphorylation genes predicts improved survival in squamous cell carcinomas of the head and neck and lung
por: Frederick, Mitchell, et al.
Publicado: (2020)

Multifactorial Contribution of Notch Signaling in Head and Neck Squamous Cell Carcinoma
por: Porcheri, Cristina, et al.
Publicado: (2019)

Novel Systemic Treatment Modalities Including Immunotherapy and Molecular Targeted Therapy for Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma
por: Ghosh, Soma, et al.
Publicado: (2022)

Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer
por: Johnson, Faye M, et al.
Publicado: (2022)

Evaluation of the anticancer activity of RIN-1, a Notch signaling modulator, in head and neck squamous cell carcinoma
por: Czerwonka, Arkadiusz, et al.
Publicado: (2023)

Shooting at Moving and Hidden Targets—Tumour Cell Plasticity and the Notch Signalling Pathway in Head and Neck Squamous Cell Carcinomas
por: Kałafut, Joanna, et al.
Publicado: (2021)

Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma
por: Broner, Esther C., et al.
Publicado: (2021)

Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck
por: Reuter, C W M, et al.
Publicado: (2007)

NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck
por: Wang, Yi-Ping, et al.
Publicado: (2021)

Somatic Mutations and Genetic Variants of NOTCH1 in Head and Neck Squamous Cell Carcinoma Occurrence and Development
por: Liu, Yu-Fan, et al.
Publicado: (2016)

Optimization of a Three-Dimensional Culturing Method for Assessing the Impact of Cisplatin on Notch Signaling in Head and Neck Squamous Cell Carcinoma (HNSCC)
por: Anameriç, Alinda, et al.
Publicado: (2023)

The Rise of FXR1: Escaping Cellular Senescence in Head and Neck Squamous Cell Carcinoma
por: Fernández, Erlinda, et al.
Publicado: (2016)

Corrigendum: Somatic Mutations and Genetic Variants of NOTCH1 in Head and Neck Squamous Cell Carcinoma Occurrence and Development
por: Liu, Yu-Fan, et al.
Publicado: (2016)

An update on angiogenesis targeting in head and neck squamous cell carcinoma
por: Micaily, Ida, et al.
Publicado: (2020)

Roles of the Wnt Signaling Pathway in Head and Neck Squamous Cell Carcinoma
por: Xie, Jing, et al.
Publicado: (2021)

The Role of Hedgehog Signaling Pathway in Head and Neck Squamous Cell Carcinoma
por: Cierpikowski, Piotr, et al.
Publicado: (2023)

Microsatellite instability in squamous cell carcinoma of the head and neck.
por: Field, J. K., et al.
Publicado: (1995)

EGFR Mutations in Head and Neck Squamous Cell Carcinoma
por: Nair, Sindhu, et al.
Publicado: (2022)

Immunotherapy in head and neck squamous cell carcinoma and rare head and neck malignancies
por: Cavalieri, Stefano, et al.
Publicado: (2021)

Head and Neck Squamous Cell Carcinoma: Epigenetic Landscape
por: Romanowska, Kamila, et al.
Publicado: (2020)

MicroRNA Deregulations in Head and Neck Squamous Cell Carcinomas
por: Chen, Dan, et al.
Publicado: (2013)

Cutaneous Squamous Cell Carcinoma of the Head and Neck
por: Gurudutt, Vivek V., et al.
Publicado: (2011)

Hypoxia in Head and Neck Squamous Cell Carcinoma
por: Li, John Zenghong, et al.
Publicado: (2012)

Immunotherapy for head and neck squamous cell carcinoma
por: Fuereder, Thorsten
Publicado: (2016)

Immunotherapy for Head and Neck Squamous Cell Carcinoma
por: Moskovitz, Jessica, et al.
Publicado: (2018)

Exosomes in Head and Neck Squamous Cell Carcinoma
por: Xiao, Cheng, et al.
Publicado: (2019)

Reciprocal activation of HEY1 and NOTCH4 under SOX2 control promotes EMT in head and neck squamous cell carcinoma
por: Fukusumi, Takahito, et al.
Publicado: (2020)

Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling
por: Aminuddin, Amnani, et al.
Publicado: (2016)

The Significance of the Dysregulation of Canonical Wnt Signaling in Head and Neck Squamous Cell Carcinomas
por: Paluszczak, Jarosław
Publicado: (2020)

The Common Costimulatory and Coinhibitory Signaling Molecules in Head and Neck Squamous Cell Carcinoma
por: Liao, Peng, et al.
Publicado: (2019)

Confluent tracheal recurrences of head and neck squamous cell carcinoma
por: Bleiberg, Benjamin Aaron, et al.
Publicado: (2019)

Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
por: Kumar, Harish A., et al.
Publicado: (2023)

PKM2 Modulation in Head and Neck Squamous Cell Carcinoma
por: Boschert, Verena, et al.
Publicado: (2022)

Outcomes of Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma
por: Dean, Nichole R., et al.
Publicado: (2011)

Potential Therapeutic Significance of Laminin in Head and Neck Squamous Carcinomas
por: Meireles Da Costa, Nathalia, et al.
Publicado: (2021)

Targeting Angiogenesis in Squamous Cell Carcinoma of the Head and Neck: Opportunities in the Immunotherapy Era
por: Saba, Nabil F., et al.
Publicado: (2022)

Alterations of GPI transamidase subunits in head and neck squamous carcinoma
por: Jiang, Wei-Wen, et al.
Publicado: (2007)

Docetaxel in the treatment of squamous cell carcinoma of the head and neck
por: Rapidis, Alexander, et al.
Publicado: (2008)

Mononuclear phagocytes in head and neck squamous cell carcinoma
por: Kross, Kenneth Wilfried, et al.
Publicado: (2009)

Molecular profiling of head and neck squamous cell carcinoma
por: Feldman, Rebecca, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_erj3nfl3qflut623uu84ta7n88