Longitudinal Analysis of Peripheral and Colonic CD161(+) CD4(+) T Cell Dysfunction in Acute HIV-1 Infection and Effects of Early Treatment Initiation

CD161 expression on CD4(+) T cells is associated with a Th17 functional phenotype, as well as with an innate capacity to respond to interleukin (IL)-12 and IL-18 without T cell receptor (TCR) stimulation. Chronic HIV-1 infection is associated with loss of the CD161(+) CD4 T cell population, and non-...

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Autores principales: Lal, Kerri G., Phuang-Ngern, Yuwadee, Suhkumvittaya, Suchada, Leeansyah, Edwin, Alrubayyi, Aljawharah, Dias, Joana, Waickman, Adam, Kim, Dohoon, Kroon, Eugène, Pinyakorn, Suteeraporn, Eller, Leigh Anne, Maciel Jr., Milton, Rerknimitr, Rungsun, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark S., Nitayaphan, Sorachai, Ake, Julie A., Vasan, Sandhya, Robb, Merlin L., Ananworanich, Jintanat, Sandberg, Johan K., Schuetz, Alexandra, Eller, Michael A., Paquin-Proulx, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764746/
https://www.ncbi.nlm.nih.gov/pubmed/33322496
http://dx.doi.org/10.3390/v12121426

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