Cargando…

Improving Stability of Tear Film Lipid Layer via Concerted Action of Two Drug Molecules: A Biophysical View

The tear film at the ocular surface is covered by a thin layer of lipids. This oily phase stabilizes the film by decreasing its surface tension and improving its viscoelastic properties. Clinically, destabilization and rupture of the tear film are related to dry eye disease and are accompanied by ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eftimov, Petar, Olżyńska, Agnieszka, Melcrová, Adéla, Georgiev, Georgi As., Daull, Philippe, Garrigue, Jean-Sebastien, Cwiklik, Lukasz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764870/ https://www.ncbi.nlm.nih.gov/pubmed/33327408 http://dx.doi.org/10.3390/ijms21249490

Ejemplares similares

Interactions of Meibum and Tears with Mucomimetic Polymers: A Hint towards the Interplay between the Layers of the Tear Film
por: Eftimov, Petar, et al.
Publicado: (2021)

Cationic Emulsion-Based Artificial Tears as a Mimic of Functional Healthy Tear Film for Restoration of Ocular Surface Homeostasis in Dry Eye Disease
por: Daull, Philippe, et al.
Publicado: (2020)

Contribution of Mucins towards the Physical Properties of the Tear Film: A Modern Update
por: Georgiev, Georgi As., et al.
Publicado: (2019)

Dynamic Aspects of Pre-Soft Contact Lens Tear Film and Their Relation to Dry Eye: Basic Science and Clinical Relevance
por: Yokoi, Norihiko, et al.
Publicado: (2023)

Organization of Lipids in the Tear Film: A Molecular-Level View
por: Wizert, Alicja, et al.
Publicado: (2014)

Surface Chemistry Interactions of Cationorm with Films by Human Meibum and Tear Film Compounds
por: Georgiev, Georgi As., et al.
Publicado: (2017)

Lipid Saturation and the Rheology of Human Tear Lipids
por: Georgiev, Georgi As., et al.
Publicado: (2019)

Safety and Tolerability of Overdosed Artificial Tears by Abraded Rabbit Corneas
por: Daull, Philippe, et al.
Publicado: (2018)

Surface Chemistry Study of the Interactions of Sesame Oil with Meibomian Films
por: Eftimov, Petar, et al.
Publicado: (2022)

Comparison of the Anti-Inflammatory Effects of Artificial Tears in a Rat Model of Corneal Scraping
por: Daull, Philippe, et al.
Publicado: (2016)

Stealthy Player in Lipid Experiments? EDTA Binding to Phosphatidylcholine Membranes Probed by Simulations and Monolayer Experiments
por: Vazdar, Katarina, et al.
Publicado: (2023)

Impact of Pollutant Ozone on the Biophysical Properties of Tear Film Lipid Layer Model Membranes
por: Keramatnejad, Mahshid, et al.
Publicado: (2023)

Effects of Lipid Saturation on the Surface Properties of Human Meibum Films
por: Nencheva, Yana, et al.
Publicado: (2018)

Surfactant Proteins SP-B and SP-C in Pulmonary Surfactant Monolayers: Physical Properties Controlled by Specific Protein–Lipid Interactions
por: Liekkinen, Juho, et al.
Publicado: (2023)

Artificial Tears: Biological Role of Their Ingredients in the Management of Dry Eye Disease
por: Labetoulle, Marc, et al.
Publicado: (2022)

The complex nature of calcium cation interactions with phospholipid bilayers
por: Melcrová, Adéla, et al.
Publicado: (2016)

Benefits of cetalkonium chloride cationic oil-in-water nanoemulsions for topical ophthalmic drug delivery
por: Daull, Philippe, et al.
Publicado: (2014)

Effect of hydrophilic polymers on the wettability, static and dynamic, of solid substrate covered by confluent monolayer of air-damaged SIRC cells
por: Eftimov, Petar, et al.
Publicado: (2015)

Impact of Air Exposure Time on the Water Contact Angles of Daily Disposable Silicone Hydrogels
por: Eftimov, Petar, et al.
Publicado: (2019)

Tail-Oxidized Cholesterol Enhances Membrane Permeability for Small Solutes
por: Olżyńska, Agnieszka, et al.
Publicado: (2020)

Surface Properties of Squalene/Meibum Films and NMR Confirmation of Squalene in Tears
por: Ivanova, Slavyana, et al.
Publicado: (2015)

Use of a Cationic Emulsion of Latanoprost to Treat Glaucoma Patients with Ocular Surface Disease: A Preclinical Review
por: Daull, Philippe, et al.
Publicado: (2023)

The Potential Role of SP-G as Surface Tension Regulator in Tear Film: From Molecular Simulations to Experimental Observations
por: Schicht, Martin, et al.
Publicado: (2022)

Successfully Improving Ocular Drug Delivery Using the Cationic Nanoemulsion, Novasorb
por: Lallemand, Frederic, et al.
Publicado: (2012)

Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
por: Daull, Philippe, et al.
Publicado: (2018)

Relationships between the material properties of silicone hydrogels: Desiccation, wettability and lubricity
por: Eftimov, Petar Borisov, et al.
Publicado: (2020)

Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model
por: Liang, Hong, et al.
Publicado: (2012)

Characteristics of dry eye patients with thick tear film lipid layers evaluated by a LipiView II interferometer
por: Lee, Yunjin, et al.
Publicado: (2021)

Turnover rate of tear-film lipid layer determined by fluorophotometry
por: Mochizuki, H, et al.
Publicado: (2009)

Decrease in Tear Film Lipid Layer Thickness in Patients with Keratoconus
por: Zhou, Wenyan, et al.
Publicado: (2022)

Effect of Model Tear Film Lipid Layer on Water Evaporation
por: Xu, Xiaojie, et al.
Publicado: (2023)

Antiviral response in vernal keratoconjunctivitis may be protective against COVID‐19
por: Leonardi, Andrea, et al.
Publicado: (2021)

Successful Detection of the Characteristics of Tear Film Breakup Appearing Immediately after Eye Opening by Videokeratography with a Newly-Developed Indicator
por: Yokoi, Norihiko, et al.
Publicado: (2023)

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis
por: Georgiev, Georgi A., et al.
Publicado: (2020)

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach
por: Mugumbate, Grace, et al.
Publicado: (2017)

Lipid layer thickness decrease due to meibomian gland dysfunction leads to tear film instability and reflex tear secretion
por: Kim, Wung Jae, et al.
Publicado: (2022)

The Properties and Role of O-Acyl-ω-hydroxy Fatty Acids and Type I-St and Type II Diesters in the Tear Film Lipid Layer Revealed by a Combined Chemistry and Biophysics Approach
por: Viitaja, Tuomo, et al.
Publicado: (2021)

Dog Tear Film Proteome In-Depth Analysis
por: Winiarczyk, Mateusz, et al.
Publicado: (2015)

Statistical Comparison of Classifiers Applied to the Interferential Tear Film Lipid Layer Automatic Classification
por: Remeseiro, B., et al.
Publicado: (2012)

Tear film proteome in age-related macular degeneration
por: Winiarczyk, Mateusz, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_oa4j9k36opbq97m5tc0jek813o