Structural Insight into the Contributions of the N-Terminus and Key Active-Site Residues to the Catalytic Efficiency of Glutamine Synthetase 2

Glutamine synthetase (GS) catalyzes the condensation of ammonia and glutamate, along with ATP, to form glutamine. Despite extensive studies on GSs from eukaryotes and prokaryotes, the roles of the N-terminus and other structural features in catalysis remain unclear. Here we report the decameric stru...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Wen-Ting, Yang, Hsin-Yu, Lin, Chih-Yu, Lee, Yi-Zong, Ma, Szu-Chin, Chen, Wei-Cheng, Yin, Hsien-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764910/
https://www.ncbi.nlm.nih.gov/pubmed/33327463
http://dx.doi.org/10.3390/biom10121671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764910/
https://www.ncbi.nlm.nih.gov/pubmed/33327463
http://dx.doi.org/10.3390/biom10121671

Ejemplares similares