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Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020

Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade 2.3.4.4, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20) belonging to clade 2.3.4.4b, was isolated from a fecal...

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Autores principales: Isoda, Norikazu, Twabela, Augustin T., Bazarragchaa, Enkhbold, Ogasawara, Kohei, Hayashi, Hirotaka, Wang, Zu-Jyun, Kobayashi, Daiki, Watanabe, Yukiko, Saito, Keisuke, Kida, Hiroshi, Sakoda, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764937/
https://www.ncbi.nlm.nih.gov/pubmed/33327524
http://dx.doi.org/10.3390/v12121439
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author Isoda, Norikazu
Twabela, Augustin T.
Bazarragchaa, Enkhbold
Ogasawara, Kohei
Hayashi, Hirotaka
Wang, Zu-Jyun
Kobayashi, Daiki
Watanabe, Yukiko
Saito, Keisuke
Kida, Hiroshi
Sakoda, Yoshihiro
author_facet Isoda, Norikazu
Twabela, Augustin T.
Bazarragchaa, Enkhbold
Ogasawara, Kohei
Hayashi, Hirotaka
Wang, Zu-Jyun
Kobayashi, Daiki
Watanabe, Yukiko
Saito, Keisuke
Kida, Hiroshi
Sakoda, Yoshihiro
author_sort Isoda, Norikazu
collection PubMed
description Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade 2.3.4.4, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20) belonging to clade 2.3.4.4b, was isolated from a fecal sample collected at a lake in Hokkaido, Japan where migratory birds rested, October 2020. In the phylogenetic trees of all eight gene segments, NP/Hok/20 fell into in the cluster of European isolates in 2020, but was distinct from the isolates in eastern Asia and Europe during the winter season of 2017–2018. The antigenic cartography indicates that the antigenicity of NP/Hok/20 was almost the same as that of previous isolates of H5 clade 2.3.4.4b, whereas the antigenic distances from NP/Hok/20 to the representative strains in clade 2.3.4.4e and to a strain in 2.3.4 were apparently distant. These data imply that HPAI virus clade 2.3.4.4b should have been delivered by bird migration despite the intercontinental distance, although it was not defined whether NP/Hok/20 was transported from Europe via Siberia where migratory birds nest in the summer season. Given the probability of perpetuation of transmission in the northern territory, periodic updates of intensive surveys on avian influenza at the global level are essential to prepare for future outbreaks of the HPAI virus.
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spelling pubmed-77649372020-12-27 Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020 Isoda, Norikazu Twabela, Augustin T. Bazarragchaa, Enkhbold Ogasawara, Kohei Hayashi, Hirotaka Wang, Zu-Jyun Kobayashi, Daiki Watanabe, Yukiko Saito, Keisuke Kida, Hiroshi Sakoda, Yoshihiro Viruses Communication Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade 2.3.4.4, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 (H5N8) (NP/Hok/20) belonging to clade 2.3.4.4b, was isolated from a fecal sample collected at a lake in Hokkaido, Japan where migratory birds rested, October 2020. In the phylogenetic trees of all eight gene segments, NP/Hok/20 fell into in the cluster of European isolates in 2020, but was distinct from the isolates in eastern Asia and Europe during the winter season of 2017–2018. The antigenic cartography indicates that the antigenicity of NP/Hok/20 was almost the same as that of previous isolates of H5 clade 2.3.4.4b, whereas the antigenic distances from NP/Hok/20 to the representative strains in clade 2.3.4.4e and to a strain in 2.3.4 were apparently distant. These data imply that HPAI virus clade 2.3.4.4b should have been delivered by bird migration despite the intercontinental distance, although it was not defined whether NP/Hok/20 was transported from Europe via Siberia where migratory birds nest in the summer season. Given the probability of perpetuation of transmission in the northern territory, periodic updates of intensive surveys on avian influenza at the global level are essential to prepare for future outbreaks of the HPAI virus. MDPI 2020-12-14 /pmc/articles/PMC7764937/ /pubmed/33327524 http://dx.doi.org/10.3390/v12121439 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Isoda, Norikazu
Twabela, Augustin T.
Bazarragchaa, Enkhbold
Ogasawara, Kohei
Hayashi, Hirotaka
Wang, Zu-Jyun
Kobayashi, Daiki
Watanabe, Yukiko
Saito, Keisuke
Kida, Hiroshi
Sakoda, Yoshihiro
Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title_full Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title_fullStr Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title_full_unstemmed Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title_short Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade 2.3.4.4b in Hokkaido, Japan, 2020
title_sort re-invasion of h5n8 high pathogenicity avian influenza virus clade 2.3.4.4b in hokkaido, japan, 2020
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764937/
https://www.ncbi.nlm.nih.gov/pubmed/33327524
http://dx.doi.org/10.3390/v12121439
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