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MEK1 Inhibitor Combined with Irradiation Reduces Migration of Breast Cancer Cells Including miR-221 and ZEB1 EMT Marker Expression
SIMPLE SUMMARY: Combined chemotherapy and radiotherapy are an effective treatment for invasive breast cancer. However, some studies suggest that such interventions may increase the risk of metastasis. Cell metastatic behavior is highly dependent on RAS-RAF-MEK pathway and its downstream target activ...
Autores principales: | Anastasov, Nataša, Hirmer, Elisabeth, Klenner, Marbod, Ott, Jessica, Falkenberg, Natalie, Bao, Xuanwen, Mutschelknaus, Lisa, Moertl, Simone, Combs, Stephanie, Atkinson, Michael J., Schmid, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7764972/ https://www.ncbi.nlm.nih.gov/pubmed/33327491 http://dx.doi.org/10.3390/cancers12123760 |
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