A Novel Platform to Test In Vivo Single Gene Dependencies in t(8,21) and t(15,17) AML Confirms Zeb2 as Leukemia Target

SIMPLE SUMMARY: Mouse models are extensively used to study human diseases, including cancer. They are particularly useful to evaluate the role of specific genes in the tumorigenic process. The platform we present allows to effectively induce in vivo silencing of any potential candidate gene in two a...

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Detalles Bibliográficos
Autores principales: De Conti, Giulia, Gruszka, Alicja M., Valli, Debora, Cammarata, Andrea Umberto, Righi, Matteo, Mazza, Massimiliano, Pelicci, Pier Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765008/
https://www.ncbi.nlm.nih.gov/pubmed/33327558
http://dx.doi.org/10.3390/cancers12123768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765008/
https://www.ncbi.nlm.nih.gov/pubmed/33327558
http://dx.doi.org/10.3390/cancers12123768

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