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Characterization of Procoagulant COAT Platelets in Patients with Glanzmann Thrombasthenia

Patients affected by the rare Glanzmann thrombasthenia (GT) suffer from defective or low levels of the platelet-associated glycoprotein (GP) IIb/IIIa, which acts as a fibrinogen receptor, and have therefore an impaired ability to aggregate platelets. Because the procoagulant activity is a dichotomou...

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Detalles Bibliográficos
Autores principales: Aliotta, Alessandro, Krüsi, Manuel, Bertaggia Calderara, Debora, Zermatten, Maxime G., Gomez, Francisco J., Batista Mesquita Sauvage, Ana P., Alberio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765091/
https://www.ncbi.nlm.nih.gov/pubmed/33327658
http://dx.doi.org/10.3390/ijms21249515