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Isoflurane Potentiation of GABA(A) Receptors Is Reduced but Not Eliminated by the β3(N265M) Mutation
Background: Mice carrying the GABA(A) receptor β3(N265M) point mutation, which renders receptors incorporating β3-subunits insensitive to many general anesthetics, have been used experimentally to link modulation of different receptor subtypes to distinct behavioral endpoints. Remarkably, however, t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765171/ https://www.ncbi.nlm.nih.gov/pubmed/33333797 http://dx.doi.org/10.3390/ijms21249534 |