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Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7
Hyperthermia (HT) treatment is a noninvasive cancer therapy, often used with radiation therapy and chemotherapy. Compared with 37 °C, 42 °C is mild heat stress for cells and produces reactive oxygen species (ROS) from mitochondria. To involve subsequent intracellular accumulation of DOX, we have pre...
Autores principales: | Terasaki, Azusa, Kurokawa, Hiromi, Ito, Hiromu, Komatsu, Yoshiki, Matano, Daisuke, Terasaki, Masahiko, Bando, Hiroko, Hara, Hisato, Matsui, Hirofumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765207/ https://www.ncbi.nlm.nih.gov/pubmed/33333736 http://dx.doi.org/10.3390/ijms21249522 |
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