Cargando…

Efficacy of Combination Chemotherapy Using a Novel Oral Chemotherapeutic Agent, FTD/TPI, with Ramucirumab Murine Version DC101 in a Mouse Syngeneic Cancer Transplantation Model

Trifluridine/tipiracil (FTD/TPI) (a.k.a. TAS-102) is a combination drug for metastatic colorectal cancer (CRC) and severely pretreated metastatic gastric/gastroesophageal junction (GEJ) cancers, comprising FTD, a thymidine-based antineoplastic nucleoside analog, and TPI, which enhances FTD bioavaila...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsunekuni, Kenta, Kawakami, Hisato, Matsuoka, Kazuaki, Nagase, Hideki, Mitani, Seiichiro, Nakagawa, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765280/ https://www.ncbi.nlm.nih.gov/pubmed/33333866 http://dx.doi.org/10.3390/jcm9124050

Ejemplares similares

Randomised phase II trial of trifluridine/tipiracil (FTD/TPI) plus ramucirumab (RAM) versus trifluridine/tipiracil for previously treated patients with advanced gastric or esophagogastric junction adenocarcinoma (RETRIEVE study, WJOG15822G)
por: Takahashi, Naoki, et al.
Publicado: (2023)

Two Cases of Long-Term Control of Metastatic Colorectal Cancer via FTD/TPI plus Bevacizumab in Elderly Patients
por: Shibutani, Masatsune, et al.
Publicado: (2018)

Emerging Targeted Therapies for HER2 Positive Gastric Cancer That Can Overcome Trastuzumab Resistance
por: Mitani, Seiichiro, et al.
Publicado: (2020)

Crystal structure of a mononuclear Ru(II) complex with a back-to-back terpyridine ligand: [RuCl(bpy)(tpy–tpy)](+)
por: Rein, Francisca N., et al.
Publicado: (2015)

The pd --> tpi+ reaction in an isobar model: angular distributions
por: Sainio, M E
Publicado: (1981)

Retrospective observational study of salvage line ramucirumab monotherapy for patients with advanced gastric cancer
por: Kawai, Sadayuki, et al.
Publicado: (2020)

Validation of the Arabic Version of the Transition Planning Inventory (TPI-AR)
por: Alnahdi, Ghaleb H., et al.
Publicado: (2023)

Amélioration d'une transmission mécanique pour un système régulé : comment un TPI de niveau CFC permet d’aborder le sujet ? (TPI)
por: Schiavo, Marco
Publicado: (2023)

Effect of a novel oral chemotherapeutic agent containing a combination of trifluridine, tipiracil and the novel triple angiokinase inhibitor nintedanib, on human colorectal cancer xenografts
por: Suzuki, Norihiko, et al.
Publicado: (2016)

A Prospective Trial Evaluating the Safety of a Shortened Infusion of Ramucirumab in Patients with Gastrointestinal Cancer
por: Hashimoto, Naoya, et al.
Publicado: (2018)

Examining the language and behavioural profile in FTD and ALS-FTD
por: Saxon, Jennifer A, et al.
Publicado: (2017)

Maintenance ramucirumab monotherapy after intolerable toxicities following docetaxel plus ramucirumab
por: Hata, Akito, et al.
Publicado: (2018)

Anxiolytic Effects of the MCH1R Antagonist TPI 1361-17
por: Lee, Cheol, et al.
Publicado: (2010)

Biomimicry Enhances Sequential Reactions of Tethered Glycolytic Enzymes, TPI and GAPDHS
por: Mukai, Chinatsu, et al.
Publicado: (2013)

Protocol of OGSG 1901: a phase II trial of ramucirumab plus irinotecan for patients with early relapsed gastric cancer during or after adjuvant docetaxel plus S − 1 therapy
por: Yamaguchi, Toshifumi, et al.
Publicado: (2022)

Robust half-metallicity and topological aspects in two-dimensional Cu-TPyB
por: Zhang, Xiaoming, et al.
Publicado: (2015)

Analyzing power of the pd --> tpi$^{+}$ reaction at 305, 330, 375 and 400 MeV
por: Lolos, G J, et al.
Publicado: (1982)

Identification of protein quality control regulators using a Drosophila model of TPI deficiency
por: Hrizo, Stacy L., et al.
Publicado: (2021)

The Individual Progress Test of Gynecology and Obstetrics Residents (TPI-GO): The Brazilian Experience by FEBRASGO
por: de Sá, Marcos Felipe Silva, et al.
Publicado: (2021)

Ramucirumab: preclinical research and clinical development
por: Aprile, Giuseppe, et al.
Publicado: (2014)

Structural and functional brain abnormalities place phenocopy frontotemporal dementia (FTD) in the FTD spectrum
por: Steketee, Rebecca M.E., et al.
Publicado: (2016)

Broad Distribution of TPI-GAPDH Fusion Proteins among Eukaryotes: Evidence for Glycolytic Reactions in the Mitochondrion?
por: Nakayama, Takuro, et al.
Publicado: (2012)

Iron in a Cage: Fixation of a Fe(II)tpy(2) Complex by Fourfold Interlinking
por: Brandl, Thomas, et al.
Publicado: (2020)

Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance
por: Liu, Peng, et al.
Publicado: (2022)

Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency
por: VanDemark, Andrew P., et al.
Publicado: (2022)

RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC
por: Nishio, Makoto, et al.
Publicado: (2022)

Inflammation in ALS/FTD pathogenesis
por: McCauley, Madelyn E., et al.
Publicado: (2018)

The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues
por: Tel, Jurjen, et al.
Publicado: (2011)

Research and Development of Atractylodes lancea (Thunb) DC. as a Promising Candidate for Cholangiocarcinoma Chemotherapeutics
por: Na-Bangchang, Kesara, et al.
Publicado: (2017)

CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure
por: Tsunekuni, Kenta, et al.
Publicado: (2019)

Clinical utility of ramucirumab in advanced gastric cancer
por: Chan, Matthew MK, et al.
Publicado: (2015)

Exploring experiences and needs of spousal carers of people with behavioural variant frontotemporal dementia (bvFTD) including those with familial FTD (fFTD): a qualitative study
por: Tookey, Sara, et al.
Publicado: (2022)

Antibiotic-free segregational plasmid stabilization in Escherichia coli owing to the knockout of triosephosphate isomerase (tpiA)
por: Velur Selvamani, Ram Shankar, et al.
Publicado: (2014)

MIX-TPI: a flexible prediction framework for TCR–pMHC interactions based on multimodal representations
por: Yang, Minghao, et al.
Publicado: (2023)

Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model
por: Dickey, Jennifer S., et al.
Publicado: (2013)

Genetic screening in sporadic ALS and FTD
por: Turner, Martin R, et al.
Publicado: (2017)

Motor Neuron Susceptibility in ALS/FTD
por: Ragagnin, Audrey M. G., et al.
Publicado: (2019)

MicroRNA-101 regulates T-cell acute lymphoblastic leukemia progression and chemotherapeutic sensitivity by targeting Notch1
por: Qian, Lu, et al.
Publicado: (2016)

Folic Acid-Metabolizing Enzymes Regulate the Antitumor Effect of 5-Fluoro-2′-Deoxyuridine in Colorectal Cancer Cell Lines
por: Tsukihara, Hiroshi, et al.
Publicado: (2016)

Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans
por: Ralser, Markus, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_ej5rrsgs4h066fanj20h81hf6g