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The PARP Inhibitor Olaparib Modulates the Transcriptional Regulatory Networks of Long Non-Coding RNAs during Vasculogenic Mimicry

In highly metastatic tumors, vasculogenic mimicry (VM) involves the acquisition by tumor cells of endothelial-like traits. Poly-(ADP-ribose) polymerase (PARP) inhibitors are currently used against tumors displaying BRCA1/2-dependent deficient homologous recombination, and they may have antimetastati...

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Detalles Bibliográficos
Autores principales: Fernández-Cortés, Mónica, Andrés-León, Eduardo, Oliver, Francisco Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765283/
https://www.ncbi.nlm.nih.gov/pubmed/33333852
http://dx.doi.org/10.3390/cells9122690

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