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Current Status on Therapeutic Molecules Targeting Siglec Receptors

The sialic acid-binding immunoglobulin-type of lectins (Siglecs) are receptors that recognize sialic acid-containing glycans. In the majority of the cases, Siglecs are expressed on immune cells and play a critical role in regulating immune cell signaling. Over the years, it has been shown that the s...

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Detalles Bibliográficos
Autores principales: Lenza, María Pia, Atxabal, Unai, Oyenarte, Iker, Jiménez-Barbero, Jesús, Ereño-Orbea, June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765293/
https://www.ncbi.nlm.nih.gov/pubmed/33333862
http://dx.doi.org/10.3390/cells9122691