Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy

Therapeutic options for non-small cell lung cancer (NSCLC) treatment have changed dramatically in recent years with the advent of novel immunotherapeutic approaches. Among these, immune checkpoint blockade (ICB) using monoclonal antibodies has shown tremendous promise in approximately 20% of patient...

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Detalles Bibliográficos
Autores principales: Ebelt, Nancy D., Zuniga, Edith, Marzagalli, Monica, Zamloot, Vic, Blazar, Bruce R., Salgia, Ravi, Manuel, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765568/
https://www.ncbi.nlm.nih.gov/pubmed/33339195
http://dx.doi.org/10.3390/biomedicines8120617

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