New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry

There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as...

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Autores principales: Papachristou, Stella, Stamatiou, Iliana, Stoian, Anca P., Papanas, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765692/
https://www.ncbi.nlm.nih.gov/pubmed/33367980
http://dx.doi.org/10.1007/s13300-020-00988-7
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author Papachristou, Stella
Stamatiou, Iliana
Stoian, Anca P.
Papanas, Nikolaos
author_facet Papachristou, Stella
Stamatiou, Iliana
Stoian, Anca P.
Papanas, Nikolaos
author_sort Papachristou, Stella
collection PubMed
description There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as underlying mechanisms. Importantly, new-onset hyperglycaemia is associated with worse prognosis in patients with COVID-19. Indeed, its prognosis may be even more sinister than in patients with pre-existing DM. More research data and knowledge are currently being collected to improve our insights into this constellation and to guide therapies in clinical reality.
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spelling pubmed-77656922020-12-28 New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry Papachristou, Stella Stamatiou, Iliana Stoian, Anca P. Papanas, Nikolaos Diabetes Ther Commentary There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as underlying mechanisms. Importantly, new-onset hyperglycaemia is associated with worse prognosis in patients with COVID-19. Indeed, its prognosis may be even more sinister than in patients with pre-existing DM. More research data and knowledge are currently being collected to improve our insights into this constellation and to guide therapies in clinical reality. Springer Healthcare 2020-12-26 2021-02 /pmc/articles/PMC7765692/ /pubmed/33367980 http://dx.doi.org/10.1007/s13300-020-00988-7 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Commentary
Papachristou, Stella
Stamatiou, Iliana
Stoian, Anca P.
Papanas, Nikolaos
New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title_full New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title_fullStr New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title_full_unstemmed New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title_short New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry
title_sort new-onset diabetes in covid-19: time to frame its fearful symmetry
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765692/
https://www.ncbi.nlm.nih.gov/pubmed/33367980
http://dx.doi.org/10.1007/s13300-020-00988-7
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