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A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil

Origanum vulgare L. is a widely used aromatic plant, especially due to its content in essential oil, mainly rich in carvacrol and thymol. The ethnopharmacological uses of Origanum vulgare L. essential oil (OEO) comprise digestive, respiratory, or dermatological disorders. The review focuses on the i...

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Autores principales: Lombrea, Adelina, Antal, Diana, Ardelean, Florina, Avram, Stefana, Pavel, Ioana Zinuca, Vlaia, Lavinia, Mut, Ana-Maria, Diaconeasa, Zorita, Dehelean, Cristina Adriana, Soica, Codruta, Danciu, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765853/
https://www.ncbi.nlm.nih.gov/pubmed/33348921
http://dx.doi.org/10.3390/ijms21249653
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author Lombrea, Adelina
Antal, Diana
Ardelean, Florina
Avram, Stefana
Pavel, Ioana Zinuca
Vlaia, Lavinia
Mut, Ana-Maria
Diaconeasa, Zorita
Dehelean, Cristina Adriana
Soica, Codruta
Danciu, Corina
author_facet Lombrea, Adelina
Antal, Diana
Ardelean, Florina
Avram, Stefana
Pavel, Ioana Zinuca
Vlaia, Lavinia
Mut, Ana-Maria
Diaconeasa, Zorita
Dehelean, Cristina Adriana
Soica, Codruta
Danciu, Corina
author_sort Lombrea, Adelina
collection PubMed
description Origanum vulgare L. is a widely used aromatic plant, especially due to its content in essential oil, mainly rich in carvacrol and thymol. The ethnopharmacological uses of Origanum vulgare L. essential oil (OEO) comprise digestive, respiratory, or dermatological disorders. The review focuses on the increasing number of recent studies investigating several biological activities of OEO. The bioactivities are in tight relation to the phytochemical profile of the essential oil, and also depend on taxonomic, climatic, and geographical characteristics of the plant material. The antibacterial, antifungal, antiparasitic, antioxidant, anti-inflammatory, antitumor, skin disorders beneficial effects, next to antihyperglycemic and anti-Alzheimer activities were reported and confirmed in multiple studies. Moreover, recent studies indicate a positive impact on skin disorders of OEO formulated as nanocarrier systems in order to improve its bioavailability and, thus, enhancing its therapeutic benefits. The review brings an up to date regarding the phytochemistry and bioactivity of Origanum vulgare L. essential oil, underlining also the most successful pharmaceutical formulation used for skin disorders.
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spelling pubmed-77658532020-12-28 A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil Lombrea, Adelina Antal, Diana Ardelean, Florina Avram, Stefana Pavel, Ioana Zinuca Vlaia, Lavinia Mut, Ana-Maria Diaconeasa, Zorita Dehelean, Cristina Adriana Soica, Codruta Danciu, Corina Int J Mol Sci Review Origanum vulgare L. is a widely used aromatic plant, especially due to its content in essential oil, mainly rich in carvacrol and thymol. The ethnopharmacological uses of Origanum vulgare L. essential oil (OEO) comprise digestive, respiratory, or dermatological disorders. The review focuses on the increasing number of recent studies investigating several biological activities of OEO. The bioactivities are in tight relation to the phytochemical profile of the essential oil, and also depend on taxonomic, climatic, and geographical characteristics of the plant material. The antibacterial, antifungal, antiparasitic, antioxidant, anti-inflammatory, antitumor, skin disorders beneficial effects, next to antihyperglycemic and anti-Alzheimer activities were reported and confirmed in multiple studies. Moreover, recent studies indicate a positive impact on skin disorders of OEO formulated as nanocarrier systems in order to improve its bioavailability and, thus, enhancing its therapeutic benefits. The review brings an up to date regarding the phytochemistry and bioactivity of Origanum vulgare L. essential oil, underlining also the most successful pharmaceutical formulation used for skin disorders. MDPI 2020-12-17 /pmc/articles/PMC7765853/ /pubmed/33348921 http://dx.doi.org/10.3390/ijms21249653 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lombrea, Adelina
Antal, Diana
Ardelean, Florina
Avram, Stefana
Pavel, Ioana Zinuca
Vlaia, Lavinia
Mut, Ana-Maria
Diaconeasa, Zorita
Dehelean, Cristina Adriana
Soica, Codruta
Danciu, Corina
A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title_full A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title_fullStr A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title_full_unstemmed A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title_short A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
title_sort recent insight regarding the phytochemistry and bioactivity of origanum vulgare l. essential oil
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765853/
https://www.ncbi.nlm.nih.gov/pubmed/33348921
http://dx.doi.org/10.3390/ijms21249653
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