Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”

Recently, in February 2020, we published a study exploring the intestinal absorption and metabolism of oleocanthal (OLC) in rats. A single-pass intestinal perfusion technique (SPIP) was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Later, comments on our publ...

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Autores principales: López-Yerena, Anallely, Vallverdú-Queralt, Anna, Mols, Raf, Augustijns, Patrick, Lamuela-Raventós, Rosa M., Escribano-Ferrer, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765908/
https://www.ncbi.nlm.nih.gov/pubmed/33348608
http://dx.doi.org/10.3390/pharmaceutics12121221
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author López-Yerena, Anallely
Vallverdú-Queralt, Anna
Mols, Raf
Augustijns, Patrick
Lamuela-Raventós, Rosa M.
Escribano-Ferrer, Elvira
author_facet López-Yerena, Anallely
Vallverdú-Queralt, Anna
Mols, Raf
Augustijns, Patrick
Lamuela-Raventós, Rosa M.
Escribano-Ferrer, Elvira
author_sort López-Yerena, Anallely
collection PubMed
description Recently, in February 2020, we published a study exploring the intestinal absorption and metabolism of oleocanthal (OLC) in rats. A single-pass intestinal perfusion technique (SPIP) was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Later, comments on our published paper were released, requesting clarification of specific data. In this detailed reply, we hope to have addressed and clarified all the concerns of A. Kaddoumi and K. El Sayed and that the scientific community will benefit from both the study and the comments it has generated.
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spelling pubmed-77659082020-12-28 Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134” López-Yerena, Anallely Vallverdú-Queralt, Anna Mols, Raf Augustijns, Patrick Lamuela-Raventós, Rosa M. Escribano-Ferrer, Elvira Pharmaceutics Reply Recently, in February 2020, we published a study exploring the intestinal absorption and metabolism of oleocanthal (OLC) in rats. A single-pass intestinal perfusion technique (SPIP) was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Later, comments on our published paper were released, requesting clarification of specific data. In this detailed reply, we hope to have addressed and clarified all the concerns of A. Kaddoumi and K. El Sayed and that the scientific community will benefit from both the study and the comments it has generated. MDPI 2020-12-17 /pmc/articles/PMC7765908/ /pubmed/33348608 http://dx.doi.org/10.3390/pharmaceutics12121221 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Reply
López-Yerena, Anallely
Vallverdú-Queralt, Anna
Mols, Raf
Augustijns, Patrick
Lamuela-Raventós, Rosa M.
Escribano-Ferrer, Elvira
Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title_full Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title_fullStr Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title_full_unstemmed Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title_short Reply to “Comment on López-Yerena et al. ‘Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats’ Pharmaceutics 2020, 12, 134”
title_sort reply to “comment on lópez-yerena et al. ‘absorption and intestinal metabolic profile of oleocanthal in rats’ pharmaceutics 2020, 12, 134”
topic Reply
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765908/
https://www.ncbi.nlm.nih.gov/pubmed/33348608
http://dx.doi.org/10.3390/pharmaceutics12121221
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