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The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems

In recent years, researchers across various fields have shown a keen interest in the exploitation of biocompatible natural polymer materials, especially the development and application of seaweed polysaccharides. Seaweed polysaccharides are a multi-component mixture composed of one or more monosacch...

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Autores principales: Zhong, Haowei, Gao, Xiaoran, Cheng, Cui, Liu, Chun, Wang, Qiaowen, Han, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765921/
https://www.ncbi.nlm.nih.gov/pubmed/33371266
http://dx.doi.org/10.3390/md18120658
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author Zhong, Haowei
Gao, Xiaoran
Cheng, Cui
Liu, Chun
Wang, Qiaowen
Han, Xiao
author_facet Zhong, Haowei
Gao, Xiaoran
Cheng, Cui
Liu, Chun
Wang, Qiaowen
Han, Xiao
author_sort Zhong, Haowei
collection PubMed
description In recent years, researchers across various fields have shown a keen interest in the exploitation of biocompatible natural polymer materials, especially the development and application of seaweed polysaccharides. Seaweed polysaccharides are a multi-component mixture composed of one or more monosaccharides, which have the functions of being anti-virus, anti-tumor, anti-mutation, anti-radiation and enhancing immunity. These biological activities allow them to be applied in various controllable and sustained anti-inflammatory and anticancer drug delivery systems, such as seaweed polysaccharide-based nanoparticles, microspheres and gels, etc. This review summarizes the advantages of alginic acid, carrageenan and other seaweed polysaccharides, and focuses on their application in gel drug delivery systems (such as nanogels, microgels and hydrogels). In addition, recent literature reports and applications of seaweed polysaccharides are also discussed.
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spelling pubmed-77659212020-12-28 The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems Zhong, Haowei Gao, Xiaoran Cheng, Cui Liu, Chun Wang, Qiaowen Han, Xiao Mar Drugs Review In recent years, researchers across various fields have shown a keen interest in the exploitation of biocompatible natural polymer materials, especially the development and application of seaweed polysaccharides. Seaweed polysaccharides are a multi-component mixture composed of one or more monosaccharides, which have the functions of being anti-virus, anti-tumor, anti-mutation, anti-radiation and enhancing immunity. These biological activities allow them to be applied in various controllable and sustained anti-inflammatory and anticancer drug delivery systems, such as seaweed polysaccharide-based nanoparticles, microspheres and gels, etc. This review summarizes the advantages of alginic acid, carrageenan and other seaweed polysaccharides, and focuses on their application in gel drug delivery systems (such as nanogels, microgels and hydrogels). In addition, recent literature reports and applications of seaweed polysaccharides are also discussed. MDPI 2020-12-21 /pmc/articles/PMC7765921/ /pubmed/33371266 http://dx.doi.org/10.3390/md18120658 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhong, Haowei
Gao, Xiaoran
Cheng, Cui
Liu, Chun
Wang, Qiaowen
Han, Xiao
The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title_full The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title_fullStr The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title_full_unstemmed The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title_short The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems
title_sort structural characteristics of seaweed polysaccharides and their application in gel drug delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765921/
https://www.ncbi.nlm.nih.gov/pubmed/33371266
http://dx.doi.org/10.3390/md18120658
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