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Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis

Background and objectives: Fatigue is one of the most disabling symptoms that limit daily life activities in persons with multiple sclerosis (pwMS). This study aimed to evaluate the effects of maximal strength training (MST) on perceived-fatigue and functional mobility in pwMS. Materials and Methods...

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Autores principales: Gomez-Illan, Ramon, Reina, Raul, Barbado, David, Sabido, Rafael, Moreno-Navarro, Pedro, Roldan, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765935/
https://www.ncbi.nlm.nih.gov/pubmed/33419374
http://dx.doi.org/10.3390/medicina56120718
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author Gomez-Illan, Ramon
Reina, Raul
Barbado, David
Sabido, Rafael
Moreno-Navarro, Pedro
Roldan, Alba
author_facet Gomez-Illan, Ramon
Reina, Raul
Barbado, David
Sabido, Rafael
Moreno-Navarro, Pedro
Roldan, Alba
author_sort Gomez-Illan, Ramon
collection PubMed
description Background and objectives: Fatigue is one of the most disabling symptoms that limit daily life activities in persons with multiple sclerosis (pwMS). This study aimed to evaluate the effects of maximal strength training (MST) on perceived-fatigue and functional mobility in pwMS. Materials and Methods: 26 participants with MS were balanced according to their pre-intervention fatigue scores and distributed into an MST group (n = 13) and a control group (CG; n = 13). The MST group completed eight weeks using high loads, evaluating detraining after ten weeks. Quadriceps and hamstring isokinetic (QPT(IK); HPT(IK)) and isometric (QPT(IM); HPT(IM)) peak torques were assessed using an isokinetic dynamometer. Effect size differences were estimated with the Hedges’ g index (d(g)). Fatigue was evaluated through the Fatigue Severity Scale (FSS), while functional mobility was assessed via the Timed Up and Go Test (TUG). Results: The MST significantly improved all the strength measurements after the intervention (Δ6.43–29.55%; p < 0.05) compared to the control group. FSS showed a significant reduction (59.97%, d(g) = 5.41, large). The MST group also reduced the TUG time (19.69%; d(g) = 0.93, large) compared to the control group. Improvements caused by the intervention did not remain after a 10-week follow-up, with decreases in strength performance from 4.40% to 13.86% (d(g) = 0.24–0.56, small to moderate), 112.08% in the FSS (d(g) = −3.88, large), and 16.93% in TUG (d(g) = −1.07, large). Conclusions: MST (up to 90% 1RM) seems to be a feasible and useful way to obtain clinically relevant improvements in the perceived-fatigue symptoms and functional mobility. Still, symptom improvements decrease after a 10-week detraining period.
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spelling pubmed-77659352020-12-28 Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis Gomez-Illan, Ramon Reina, Raul Barbado, David Sabido, Rafael Moreno-Navarro, Pedro Roldan, Alba Medicina (Kaunas) Article Background and objectives: Fatigue is one of the most disabling symptoms that limit daily life activities in persons with multiple sclerosis (pwMS). This study aimed to evaluate the effects of maximal strength training (MST) on perceived-fatigue and functional mobility in pwMS. Materials and Methods: 26 participants with MS were balanced according to their pre-intervention fatigue scores and distributed into an MST group (n = 13) and a control group (CG; n = 13). The MST group completed eight weeks using high loads, evaluating detraining after ten weeks. Quadriceps and hamstring isokinetic (QPT(IK); HPT(IK)) and isometric (QPT(IM); HPT(IM)) peak torques were assessed using an isokinetic dynamometer. Effect size differences were estimated with the Hedges’ g index (d(g)). Fatigue was evaluated through the Fatigue Severity Scale (FSS), while functional mobility was assessed via the Timed Up and Go Test (TUG). Results: The MST significantly improved all the strength measurements after the intervention (Δ6.43–29.55%; p < 0.05) compared to the control group. FSS showed a significant reduction (59.97%, d(g) = 5.41, large). The MST group also reduced the TUG time (19.69%; d(g) = 0.93, large) compared to the control group. Improvements caused by the intervention did not remain after a 10-week follow-up, with decreases in strength performance from 4.40% to 13.86% (d(g) = 0.24–0.56, small to moderate), 112.08% in the FSS (d(g) = −3.88, large), and 16.93% in TUG (d(g) = −1.07, large). Conclusions: MST (up to 90% 1RM) seems to be a feasible and useful way to obtain clinically relevant improvements in the perceived-fatigue symptoms and functional mobility. Still, symptom improvements decrease after a 10-week detraining period. MDPI 2020-12-20 /pmc/articles/PMC7765935/ /pubmed/33419374 http://dx.doi.org/10.3390/medicina56120718 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gomez-Illan, Ramon
Reina, Raul
Barbado, David
Sabido, Rafael
Moreno-Navarro, Pedro
Roldan, Alba
Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title_full Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title_fullStr Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title_full_unstemmed Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title_short Effects of Maximal Strength Training on Perceived-Fatigue and Functional Mobility in Persons with Relapsing-Remitting Multiple Sclerosis
title_sort effects of maximal strength training on perceived-fatigue and functional mobility in persons with relapsing-remitting multiple sclerosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765935/
https://www.ncbi.nlm.nih.gov/pubmed/33419374
http://dx.doi.org/10.3390/medicina56120718
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