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Molecular and Biochemical Basis of Fluoroquinolones-Induced Phototoxicity—The Study of Antioxidant System in Human Melanocytes Exposed to UV-A Radiation

Phototoxicity of fluoroquinolones is connected with oxidative stress induction. Lomefloxacin (8-halogenated derivative) is considered the most phototoxic fluoroquinolone and moxifloxacin (8-methoxy derivative) the least. Melanin pigment may protect cells from oxidative damage. On the other hand, flu...

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Detalles Bibliográficos
Autores principales: Kowalska, Justyna, Banach, Klaudia, Rok, Jakub, Beberok, Artur, Rzepka, Zuzanna, Wrześniok, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765951/
https://www.ncbi.nlm.nih.gov/pubmed/33352719
http://dx.doi.org/10.3390/ijms21249714