High Levels of Receptor Tyrosine Kinases in CCM3-Deficient Cells Increase Their Susceptibility to Tyrosine Kinase Inhibition

Cerebral cavernous malformations (CCMs) are vascular malformations that can be the result of the deficiency of one of the CCM genes. Their only present treatment is surgical removal, which is not always possible, and an alternative pharmacological strategy to eliminate them is actively sought. We ha...

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Detalles Bibliográficos
Autores principales: Sartages, Miriam, Floridia, Ebel, García-Colomer, Mar, Iglesias, Cristina, Macía, Manuel, Peñas, Patricia, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Pombo, Celia M., Zalvide, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766026/
https://www.ncbi.nlm.nih.gov/pubmed/33348877
http://dx.doi.org/10.3390/biomedicines8120624

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