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Current Trends in Cancer Immunotherapy
The search for an effective drug to treat oncological diseases, which have become the main scourge of mankind, has generated a lot of methods for studying this affliction. It has also become a serious challenge for scientists and clinicians who have needed to invent new ways of overcoming the proble...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766207/ https://www.ncbi.nlm.nih.gov/pubmed/33348704 http://dx.doi.org/10.3390/biomedicines8120621 |
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author | Filin, Ivan Y. Solovyeva, Valeriya V. Kitaeva, Kristina V. Rutland, Catrin S. Rizvanov, Albert A. |
author_facet | Filin, Ivan Y. Solovyeva, Valeriya V. Kitaeva, Kristina V. Rutland, Catrin S. Rizvanov, Albert A. |
author_sort | Filin, Ivan Y. |
collection | PubMed |
description | The search for an effective drug to treat oncological diseases, which have become the main scourge of mankind, has generated a lot of methods for studying this affliction. It has also become a serious challenge for scientists and clinicians who have needed to invent new ways of overcoming the problems encountered during treatments, and have also made important discoveries pertaining to fundamental issues relating to the emergence and development of malignant neoplasms. Understanding the basics of the human immune system interactions with tumor cells has enabled new cancer immunotherapy strategies. The initial successes observed in immunotherapy led to new methods of treating cancer and attracted the attention of the scientific and clinical communities due to the prospects of these methods. Nevertheless, there are still many problems that prevent immunotherapy from calling itself an effective drug in the fight against malignant neoplasms. This review examines the current state of affairs for each immunotherapy method, the effectiveness of the strategies under study, as well as possible ways to overcome the problems that have arisen and increase their therapeutic potentials. |
format | Online Article Text |
id | pubmed-7766207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77662072020-12-28 Current Trends in Cancer Immunotherapy Filin, Ivan Y. Solovyeva, Valeriya V. Kitaeva, Kristina V. Rutland, Catrin S. Rizvanov, Albert A. Biomedicines Review The search for an effective drug to treat oncological diseases, which have become the main scourge of mankind, has generated a lot of methods for studying this affliction. It has also become a serious challenge for scientists and clinicians who have needed to invent new ways of overcoming the problems encountered during treatments, and have also made important discoveries pertaining to fundamental issues relating to the emergence and development of malignant neoplasms. Understanding the basics of the human immune system interactions with tumor cells has enabled new cancer immunotherapy strategies. The initial successes observed in immunotherapy led to new methods of treating cancer and attracted the attention of the scientific and clinical communities due to the prospects of these methods. Nevertheless, there are still many problems that prevent immunotherapy from calling itself an effective drug in the fight against malignant neoplasms. This review examines the current state of affairs for each immunotherapy method, the effectiveness of the strategies under study, as well as possible ways to overcome the problems that have arisen and increase their therapeutic potentials. MDPI 2020-12-17 /pmc/articles/PMC7766207/ /pubmed/33348704 http://dx.doi.org/10.3390/biomedicines8120621 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Filin, Ivan Y. Solovyeva, Valeriya V. Kitaeva, Kristina V. Rutland, Catrin S. Rizvanov, Albert A. Current Trends in Cancer Immunotherapy |
title | Current Trends in Cancer Immunotherapy |
title_full | Current Trends in Cancer Immunotherapy |
title_fullStr | Current Trends in Cancer Immunotherapy |
title_full_unstemmed | Current Trends in Cancer Immunotherapy |
title_short | Current Trends in Cancer Immunotherapy |
title_sort | current trends in cancer immunotherapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766207/ https://www.ncbi.nlm.nih.gov/pubmed/33348704 http://dx.doi.org/10.3390/biomedicines8120621 |
work_keys_str_mv | AT filinivany currenttrendsincancerimmunotherapy AT solovyevavaleriyav currenttrendsincancerimmunotherapy AT kitaevakristinav currenttrendsincancerimmunotherapy AT rutlandcatrins currenttrendsincancerimmunotherapy AT rizvanovalberta currenttrendsincancerimmunotherapy |