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Analgesic Efficacy of a Combination of Fentanyl and a Japanese Herbal Medicine “Yokukansan” in Rats with Acute Inflammatory Pain

Background: Fentanyl can induce acute opioid tolerance and postoperative hyperalgesia when administered at a single high dose; thus, this study examined the analgesic efficacy of a combination of fentanyl and Yokukansan (YKS). Methods: Rats were divided into control, formalin-injected (FOR), YKS-tre...

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Detalles Bibliográficos
Autores principales:	Akanuma, Yuko, Kato, Mami, Takayama, Yasunori, Ikemoto, Hideshi, Adachi, Naoki, Ohashi, Yusuke, Yogi, Wakako, Okumo, Takayuki, Tsukada, Mana, Sunagawa, Masataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766210/ https://www.ncbi.nlm.nih.gov/pubmed/33348580 http://dx.doi.org/10.3390/medicines7120075

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