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SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)

Serosurveys may help to assess the transmission dynamics in high-risk groups. The aim of the study was to assess the SARS-CoV-2 antibody seroprevalence in people who had performed essential activities during the lock-down period in the Province of Prato (Italy), and to evaluate the risk of exposure...

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Autores principales: Lastrucci, Vieri, Lorini, Chiara, Del Riccio, Marco, Gori, Eleonora, Chiesi, Fabrizio, Sartor, Gino, Zanella, Beatrice, Boccalini, Sara, Bechini, Angela, Puggelli, Francesco, Bonanni, Paolo, Bonaccorsi, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766502/
https://www.ncbi.nlm.nih.gov/pubmed/33352743
http://dx.doi.org/10.3390/vaccines8040778
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author Lastrucci, Vieri
Lorini, Chiara
Del Riccio, Marco
Gori, Eleonora
Chiesi, Fabrizio
Sartor, Gino
Zanella, Beatrice
Boccalini, Sara
Bechini, Angela
Puggelli, Francesco
Bonanni, Paolo
Bonaccorsi, Guglielmo
author_facet Lastrucci, Vieri
Lorini, Chiara
Del Riccio, Marco
Gori, Eleonora
Chiesi, Fabrizio
Sartor, Gino
Zanella, Beatrice
Boccalini, Sara
Bechini, Angela
Puggelli, Francesco
Bonanni, Paolo
Bonaccorsi, Guglielmo
author_sort Lastrucci, Vieri
collection PubMed
description Serosurveys may help to assess the transmission dynamics in high-risk groups. The aim of the study was to assess the SARS-CoV-2 antibody seroprevalence in people who had performed essential activities during the lock-down period in the Province of Prato (Italy), and to evaluate the risk of exposure to SARS-CoV-2 according to the type of service. All the workers and volunteers of the Civil Protection, employees of the municipalities, and all the staff of the Health Authority of the Province of Prato were invited to be tested with a rapid serological test. A total of 4656 participants were tested. SARS-CoV-2 antibodies were found in 138 (2.96%) cases. The seroprevalence in health care workers, in participants involved in essential support services and in those who worked from home were 4.1%, 1.4% and 1.0%, respectively. Health care workers experienced higher odds of seropositivity (OR 4.38, 95%CI 2.19–10.41) than participants who were assigned to work-from-home; no significant seropositivity differences were observed between support services and work-from-home groups. A low circulation of SARS-CoV-2 was observed among participants performing different essential activities. Findings highlighted the risk of in-hospital transmission in healthcare workers and that community support services may increase the risk of seropositivity to a limited extent in low incidence areas.
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spelling pubmed-77665022020-12-28 SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy) Lastrucci, Vieri Lorini, Chiara Del Riccio, Marco Gori, Eleonora Chiesi, Fabrizio Sartor, Gino Zanella, Beatrice Boccalini, Sara Bechini, Angela Puggelli, Francesco Bonanni, Paolo Bonaccorsi, Guglielmo Vaccines (Basel) Article Serosurveys may help to assess the transmission dynamics in high-risk groups. The aim of the study was to assess the SARS-CoV-2 antibody seroprevalence in people who had performed essential activities during the lock-down period in the Province of Prato (Italy), and to evaluate the risk of exposure to SARS-CoV-2 according to the type of service. All the workers and volunteers of the Civil Protection, employees of the municipalities, and all the staff of the Health Authority of the Province of Prato were invited to be tested with a rapid serological test. A total of 4656 participants were tested. SARS-CoV-2 antibodies were found in 138 (2.96%) cases. The seroprevalence in health care workers, in participants involved in essential support services and in those who worked from home were 4.1%, 1.4% and 1.0%, respectively. Health care workers experienced higher odds of seropositivity (OR 4.38, 95%CI 2.19–10.41) than participants who were assigned to work-from-home; no significant seropositivity differences were observed between support services and work-from-home groups. A low circulation of SARS-CoV-2 was observed among participants performing different essential activities. Findings highlighted the risk of in-hospital transmission in healthcare workers and that community support services may increase the risk of seropositivity to a limited extent in low incidence areas. MDPI 2020-12-19 /pmc/articles/PMC7766502/ /pubmed/33352743 http://dx.doi.org/10.3390/vaccines8040778 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lastrucci, Vieri
Lorini, Chiara
Del Riccio, Marco
Gori, Eleonora
Chiesi, Fabrizio
Sartor, Gino
Zanella, Beatrice
Boccalini, Sara
Bechini, Angela
Puggelli, Francesco
Bonanni, Paolo
Bonaccorsi, Guglielmo
SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title_full SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title_fullStr SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title_full_unstemmed SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title_short SARS-CoV-2 Seroprevalence Survey in People Involved in Different Essential Activities during the General Lock-Down Phase in the Province of Prato (Tuscany, Italy)
title_sort sars-cov-2 seroprevalence survey in people involved in different essential activities during the general lock-down phase in the province of prato (tuscany, italy)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766502/
https://www.ncbi.nlm.nih.gov/pubmed/33352743
http://dx.doi.org/10.3390/vaccines8040778
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