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Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide
SIMPLE SUMMARY: Glioblastoma (GBM) resistance to standard treatment is driven by stem-like cell behavior and epithelial-like-mesenchymal transition. The main purpose of this paper was to functionally validate a novel discovered pharmacological strategy to treat GBM, the dual mTOR pathway inhibitor R...
Autores principales: | Vargas-Toscano, Andres, Nickel, Ann-Christin, Li, Guanzhang, Kamp, Marcel Alexander, Muhammad, Sajjad, Leprivier, Gabriel, Fritsche, Ellen, Barker, Roger A., Sabel, Michael, Steiger, Hans-Jakob, Zhang, Wei, Hänggi, Daniel, Kahlert, Ulf Dietrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766508/ https://www.ncbi.nlm.nih.gov/pubmed/33371210 http://dx.doi.org/10.3390/cancers12123859 |
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