Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for Pharmacogenetics

Personalized medicine strives to optimize drug treatment for the individual patient by taking into account both genetic and non-genetic factors for drug response. Inflammation is one of the non-genetic factors that has been shown to greatly affect the metabolism of drugs—primarily through inhibition...

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Detalles Bibliográficos
Autores principales: de Jong, Laura M., Jiskoot, Wim, Swen, Jesse J., Manson, Martijn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766585/
https://www.ncbi.nlm.nih.gov/pubmed/33339226
http://dx.doi.org/10.3390/genes11121509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766585/
https://www.ncbi.nlm.nih.gov/pubmed/33339226
http://dx.doi.org/10.3390/genes11121509

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