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An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity

Cisplatin is widely used to treat various types of cancers, but it is often limited by nephrotoxicity. Here, we employed an integrated in silico and in vivo approach to identify potential treatments for cisplatin-induced nephrotoxicity (CIN). Using publicly available mouse kidney and human kidney or...

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Detalles Bibliográficos
Autores principales: Wakai, Eri, Suzumura, Yuya, Ikemura, Kenji, Mizuno, Toshiro, Watanabe, Masatoshi, Takeuchi, Kazuhiko, Nishimura, Yuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766590/
https://www.ncbi.nlm.nih.gov/pubmed/33419241
http://dx.doi.org/10.3390/ph13120480

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