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An Integrated In Silico and In Vivo Approach to Identify Protective Effects of Palonosetron in Cisplatin-Induced Nephrotoxicity
Cisplatin is widely used to treat various types of cancers, but it is often limited by nephrotoxicity. Here, we employed an integrated in silico and in vivo approach to identify potential treatments for cisplatin-induced nephrotoxicity (CIN). Using publicly available mouse kidney and human kidney or...
Autores principales: | Wakai, Eri, Suzumura, Yuya, Ikemura, Kenji, Mizuno, Toshiro, Watanabe, Masatoshi, Takeuchi, Kazuhiko, Nishimura, Yuhei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766590/ https://www.ncbi.nlm.nih.gov/pubmed/33419241 http://dx.doi.org/10.3390/ph13120480 |
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