Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity

Lipid catabolism represents an Achilles heel in prostate cancer (PCa) that can be exploited for therapy. CPT1A regulates the entry of fatty acids into the mitochondria for beta-oxidation and its inhibition has been shown to decrease PCa growth. In this study, we examined the pharmacological blockade...

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Detalles Bibliográficos
Autores principales: Guth, Amanda, Monk, Emily, Agarwal, Rajesh, Bergman, Bryan C., Zemski-Berry, Karin A., Minic, Angela, Jordan, Kimberly, Schlaepfer, Isabel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766808/
https://www.ncbi.nlm.nih.gov/pubmed/33352903
http://dx.doi.org/10.3390/ijms21249660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766808/
https://www.ncbi.nlm.nih.gov/pubmed/33352903
http://dx.doi.org/10.3390/ijms21249660

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