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Lactate Metabolism in Breast Cancer Microenvironment: Contribution Focused on Associated Adipose Tissue and Obesity

Metabolic reprogramming that favors high glycolytic flux with lactate production in normoxia is among cancer hallmarks. Lactate is an essential oncometabolite regulating cellular redox homeostasis, energy substrate partitioning, and intracellular signaling. Moreover, malignant phenotype’s chief char...

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Detalles Bibliográficos
Autores principales: Kalezic, Andjelika, Udicki, Mirjana, Srdic Galic, Biljana, Aleksic, Marija, Korac, Aleksandra, Jankovic, Aleksandra, Korac, Bato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766866/
https://www.ncbi.nlm.nih.gov/pubmed/33353120
http://dx.doi.org/10.3390/ijms21249676