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Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer
The histone methyltransferase SETD8, which methylates the lysine 20 of histone H4 (H4K20), is reportedly involved in human carcinogenesis along with nonhistone proteins such as p53. However, its expression profiles and functions in the context of high-grade serous ovarian carcinoma (HGSOC) are still...
Autores principales: | Wada, Miku, Kukita, Asako, Sone, Kenbun, Hamamoto, Ryuji, Kaneko, Syuzo, Komatsu, Masaaki, Takahashi, Yu, Inoue, Futaba, Kojima, Machiko, Honjoh, Harunori, Taguchi, Ayumi, Kashiyama, Tomoko, Miyamoto, Yuichiro, Tanikawa, Michihiro, Tsuruga, Tetsushi, Mori-Uchino, Mayuyo, Wada-Hiraike, Osamu, Osuga, Yutaka, Fujii, Tomoyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766894/ https://www.ncbi.nlm.nih.gov/pubmed/33339442 http://dx.doi.org/10.3390/biom10121686 |
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