Cargando…
Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats
A promising therapeutic strategy for amyotrophic lateral sclerosis (ALS) treatment is stem cell therapy. Neural progenitors derived from induced pluripotent cells (NP-iPS) might rescue or replace dying motoneurons (MNs). However, the mechanisms responsible for the beneficial effect are not fully und...
Autores principales: | Forostyak, Serhiy, Forostyak, Oksana, Kwok, Jessica C. F., Romanyuk, Nataliya, Rehorova, Monika, Kriska, Jan, Dayanithi, Govindan, Raha-Chowdhury, Ruma, Jendelova, Pavla, Anderova, Miroslava, Fawcett, James W., Sykova, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766921/ https://www.ncbi.nlm.nih.gov/pubmed/33339362 http://dx.doi.org/10.3390/ijms21249593 |
Ejemplares similares
-
Intrathecal Delivery of Mesenchymal Stromal Cells Protects the Structure of Altered Perineuronal Nets in SOD1 Rats and Amends the Course of ALS
por: Forostyak, Serhiy, et al.
Publicado: (2014) -
Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons
por: Cocks, Graham, et al.
Publicado: (2013) -
Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS
por: Viero, Cedric, et al.
Publicado: (2014) -
Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation
por: Dayanithi, Govindan, et al.
Publicado: (2018) -
Comparison of intraspinal and intrathecal implantation of induced pluripotent stem cell-derived neural precursors for the treatment of spinal cord injury in rats
por: Amemori, Takashi, et al.
Publicado: (2015)