Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model

COASY protein-associated neurodegeneration (CoPAN) is a rare but devastating genetic autosomal recessive disorder of inborn error of CoA metabolism, which shares with pantothenate kinase-associated neurodegeneration (PKAN) similar features, such as dystonia, parkinsonian traits, cognitive impairment...

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Detalles Bibliográficos
Autores principales: Di Meo, Ivano, Cavestro, Chiara, Pedretti, Silvia, Fu, Tingting, Ligorio, Simona, Manocchio, Antonello, Lavermicocca, Lucrezia, Santambrogio, Paolo, Ripamonti, Maddalena, Levi, Sonia, Ayciriex, Sophie, Mitro, Nico, Tiranti, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7766928/
https://www.ncbi.nlm.nih.gov/pubmed/33352696
http://dx.doi.org/10.3390/ijms21249707

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