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Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

Microglia controls the immune system response in the brain. Specifically, the activation and dysregulation of the NLRP3 inflammasome is responsible for the initiation of the inflammatory process through IL-1β and IL-18 release. In this work, we have focused on studying the effect of melatonin on the...

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Detalles Bibliográficos
Autores principales:	Farré-Alins, Víctor, Narros-Fernández, Paloma, Palomino-Antolín, Alejandra, Decouty-Pérez, Céline, Lopez-Rodriguez, Ana Belen, Parada, Esther, Muñoz-Montero, Alicia, Gómez-Rangel, Vanessa, López-Muñoz, Francisco, Ramos, Eva, González-Rodríguez, Águeda, Gandía, Luis, Romero, Alejandro, Egea, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767051/ https://www.ncbi.nlm.nih.gov/pubmed/33353046 http://dx.doi.org/10.3390/antiox9121299

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