Cargando…

Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients

SIMPLE SUMMARY: We investigated the clinical significance of a recently identified association between insulin-like growth factor binding protein 3 (IGFBP-3), that plays a key role in breast cancer progression, and glucose-regulated protein 78 (GRP78). We report a direct correlation between the expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zielinska, Hanna A., Daly, Carl S., Alghamdi, Ahmad, Bahl, Amit, Sohail, Muhammed, White, Paul, Dean, Sarah R., Holly, Jeff M. P., Perks, Claire M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767108/ https://www.ncbi.nlm.nih.gov/pubmed/33352865 http://dx.doi.org/10.3390/cancers12123821

Ejemplares similares

Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor–binding protein 3?
por: Zielinska, Hanna A, et al.
Publicado: (2015)

GRP78 in lung cancer
por: Xia, Shengkai, et al.
Publicado: (2021)

Intrinsic, Pro-Apoptotic Effects of IGFBP-3 on Breast Cancer Cells are Reversible: Involvement of PKA, Rho, and Ceramide
por: Perks, Claire M., et al.
Publicado: (2011)

Mitochondrial metabolic regulation by GRP78
por: Prasad, Manoj, et al.
Publicado: (2017)

Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014)

Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer
por: Niu, Zheyu, et al.
Publicado: (2015)

IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2020)

Hyperglycaemia-induced resistance to Docetaxel is negated by metformin: a role for IGFBP-2
por: Biernacka, K M, et al.
Publicado: (2016)

Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes
por: Tsurusawa, Naoko, et al.
Publicado: (2022)

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
por: Ibanez, Jorge, et al.
Publicado: (2023)

Correction: IGF-1 and hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells
por: Mansor, Rehanna, et al.
Publicado: (2023)

Grp78 promotes the invasion of hepatocellular carcinoma
por: Su, Rongjian, et al.
Publicado: (2010)

GRP78 at the Centre of the Stage in Cancer and Neuroprotection
por: Casas, Caty
Publicado: (2017)

Targeting the GRP78 Pathway for Cancer Therapy
por: Lu, Guanhua, et al.
Publicado: (2020)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017)

IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells
por: Tang, Zhen, et al.
Publicado: (2019)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

Involvement of Membrane GRP78 in Trophoblastic Cell Fusion
por: Fradet, Sarah, et al.
Publicado: (2012)

The Interplay between Glucose-Regulated Protein 78 (GRP78) and Steroids in the Reproductive System
por: Hebert-Schuster, Marylise, et al.
Publicado: (2018)

High expression of glucose-regulated protein 78 (GRP78) is associated with metastasis and poor prognosis in patients with esophageal squamous cell carcinoma
por: Ren, Peng, et al.
Publicado: (2017)

Glucose- regulated protein 78 (GRP78) in renal cell carcinoma: A novel biomarker for predicting tumor behavior
por: Kumar, Manoj, et al.
Publicado: (2021)

Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease
por: Takahashi, Shin-Ichiro, et al.
Publicado: (2022)

The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
por: Carlos, Anthony J., et al.
Publicado: (2021)

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth
por: Ho, Kuen Yao, et al.
Publicado: (2013)

Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells
por: Lu, Tong, et al.
Publicado: (2019)

A role for androgen receptor variant 7 in sensitivity to therapy: Involvement of IGFBP-2 and FOXA1
por: Biernacka, K.M., et al.
Publicado: (2023)

Cell surface GRP78: A potential marker of good prognosis and response to chemotherapy in breast cancer
por: YERUSHALMI, RINAT, et al.
Publicado: (2015)

GRP78 inhibits macrophage adhesion via SR-A
por: Bai, Hui, et al.
Publicado: (2014)

Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs
por: Hughes, Scott J., et al.
Publicado: (2016)

The meta and bioinformatics analysis of GRP78 expression in gastric cancer
por: Zheng, Hua-Chuan, et al.
Publicado: (2017)

GRP78 Is a Targetable Receptor on Cancer and Stromal Cells
por: Araujo, Nathalia, et al.
Publicado: (2018)

GRP78 targeting: Hitting two birds with a stone
por: Elfiky, Abdo A., et al.
Publicado: (2020)

GRP 78 antibodies are associated with clinical phenotype in neuromyelitis optica
por: Shimizu, Fumitaka, et al.
Publicado: (2019)

ILDR2 stabilization is regulated by its interaction with GRP78
por: Watanabe, Kazuhisa, et al.
Publicado: (2021)

COVID-19, Obesity, and GRP78: Unraveling the Pathological Link
por: Shin, Jihoon, et al.
Publicado: (2023)

Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2
por: Holly, Jeff M. P., et al.
Publicado: (2017)

Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases
por: Gonzalez-Gronow, Mario, et al.
Publicado: (2022)

A Role for ER-Beta in the Effects of Low-Density Lipoprotein Cholesterol and 27-Hydroxycholesterol on Breast Cancer Progression: Involvement of the IGF Signalling Pathway?
por: Mashat, Reham M., et al.
Publicado: (2021)

PGK1 and GRP78 overexpression correlates with clinical significance and poor prognosis in Chinese endometrial cancer patients
por: Guo, Suiqun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_isb4ot4o1j6ak8vpfb4to833et