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Quantification of Trastuzumab–HER2 Engagement In Vitro and In Vivo
Human EGF Receptor 2 (HER2) is an important oncogene driving aggressive metastatic growth in up to 20% of breast cancer tumors. At the same time, it presents a target for passive immunotherapy such as trastuzumab (TZM). Although TZM has been widely used clinically since 1998, not all eligible patien...
Autores principales: | Rudkouskaya, Alena, Smith, Jason T., Intes, Xavier, Barroso, Margarida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767145/ https://www.ncbi.nlm.nih.gov/pubmed/33348564 http://dx.doi.org/10.3390/molecules25245976 |
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