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Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review
The blood-brain barrier (BBB), which is composed of endothelial cells, pericytes, astrocytes, and neurons, separates the brain extracellular fluid from the circulating blood, and maintains the homeostasis of the central nervous system (CNS). The BBB endothelial cells have well-developed tight juncti...
Autores principales: | Tachibana, Keisuke, Iwashita, Yumi, Wakayama, Erika, Nishino, Itsuki, Nishikaji, Taiki, Kondoh, Masuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767277/ https://www.ncbi.nlm.nih.gov/pubmed/33352631 http://dx.doi.org/10.3390/pharmaceutics12121236 |
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