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Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients—A Controlled Clinical Trial

Background: This controlled clinical study aimed to investigate the impact of obesity on plasma and tissue pharmacokinetics of meropenem. Methods: Obese (body mass index (BMI) ≥ 35 kg/m(2)) and age-/sex-matched nonobese (18.5 kg/m(2) ≥ BMI ≤ 30 kg/m(2)) surgical patients received a short-term infusi...

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Detalles Bibliográficos
Autores principales:	Simon, Philipp, Petroff, David, Busse, David, Heyne, Jana, Girrbach, Felix, Dietrich, Arne, Kratzer, Alexander, Zeitlinger, Markus, Kloft, Charlotte, Kees, Frieder, Wrigge, Hermann, Dorn, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767385/ https://www.ncbi.nlm.nih.gov/pubmed/33371322 http://dx.doi.org/10.3390/antibiotics9120931

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