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Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda

Preventive chemotherapy (PC) is a WHO-recommended core intervention measures to eliminate Soil-Transmitted Helminths (STH) as a public health problem by 2020, defined as a reduction in prevalence to <1% of moderate or high-intensity infection. We conducted a cross-sectional study to investigate t...

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Autores principales: Kabatende, Joseph, Mugisha, Michael, Ntirenganya, Lazare, Barry, Abbie, Ruberanziza, Eugene, Mbonigaba, Jean Bosco, Bergman, Ulf, Bienvenu, Emile, Aklillu, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767502/
https://www.ncbi.nlm.nih.gov/pubmed/33371488
http://dx.doi.org/10.3390/pathogens9121076
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author Kabatende, Joseph
Mugisha, Michael
Ntirenganya, Lazare
Barry, Abbie
Ruberanziza, Eugene
Mbonigaba, Jean Bosco
Bergman, Ulf
Bienvenu, Emile
Aklillu, Eleni
author_facet Kabatende, Joseph
Mugisha, Michael
Ntirenganya, Lazare
Barry, Abbie
Ruberanziza, Eugene
Mbonigaba, Jean Bosco
Bergman, Ulf
Bienvenu, Emile
Aklillu, Eleni
author_sort Kabatende, Joseph
collection PubMed
description Preventive chemotherapy (PC) is a WHO-recommended core intervention measures to eliminate Soil-Transmitted Helminths (STH) as a public health problem by 2020, defined as a reduction in prevalence to <1% of moderate or high-intensity infection. We conducted a cross-sectional study to investigate the prevalence, intensity, and correlates of STH after a decade of PC in Rwanda. A total of 4998 school children (5–15 years old) from four districts along Lake Kivu in the western province were screened for STH using Kato-Katz. The overall prevalence of Soil-transmitted helminths among school children was 77.7% (range between districts = 54% to 92%). Trichirus trichiura was the most common STH (66.8%, range between districts = 23% to 88.2%), followed by Ascaris lumbricoides (49.9%, range between district = 28.5% to 63.3%) and hookworms (1.9%, range between districts = 0.6% to 2.9%). The prevalence of single, double and of triple parasite coinfection were 48.6%, 50.3%, and 1.1%, respectively. The overall prevalence of moderate or high-intensity infection for Trichirus trichiura and Ascaris lumbricoides was 7.1% and 13.9, respectively. Multivariate logistic regression model revealed that male sex, district, stunting, and schistosomiasis coinfection as significant predictors of STH infection. Despite a decade of PC implementation, STH remain a significant public health problem in Rwanda.
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spelling pubmed-77675022020-12-28 Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda Kabatende, Joseph Mugisha, Michael Ntirenganya, Lazare Barry, Abbie Ruberanziza, Eugene Mbonigaba, Jean Bosco Bergman, Ulf Bienvenu, Emile Aklillu, Eleni Pathogens Article Preventive chemotherapy (PC) is a WHO-recommended core intervention measures to eliminate Soil-Transmitted Helminths (STH) as a public health problem by 2020, defined as a reduction in prevalence to <1% of moderate or high-intensity infection. We conducted a cross-sectional study to investigate the prevalence, intensity, and correlates of STH after a decade of PC in Rwanda. A total of 4998 school children (5–15 years old) from four districts along Lake Kivu in the western province were screened for STH using Kato-Katz. The overall prevalence of Soil-transmitted helminths among school children was 77.7% (range between districts = 54% to 92%). Trichirus trichiura was the most common STH (66.8%, range between districts = 23% to 88.2%), followed by Ascaris lumbricoides (49.9%, range between district = 28.5% to 63.3%) and hookworms (1.9%, range between districts = 0.6% to 2.9%). The prevalence of single, double and of triple parasite coinfection were 48.6%, 50.3%, and 1.1%, respectively. The overall prevalence of moderate or high-intensity infection for Trichirus trichiura and Ascaris lumbricoides was 7.1% and 13.9, respectively. Multivariate logistic regression model revealed that male sex, district, stunting, and schistosomiasis coinfection as significant predictors of STH infection. Despite a decade of PC implementation, STH remain a significant public health problem in Rwanda. MDPI 2020-12-21 /pmc/articles/PMC7767502/ /pubmed/33371488 http://dx.doi.org/10.3390/pathogens9121076 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kabatende, Joseph
Mugisha, Michael
Ntirenganya, Lazare
Barry, Abbie
Ruberanziza, Eugene
Mbonigaba, Jean Bosco
Bergman, Ulf
Bienvenu, Emile
Aklillu, Eleni
Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title_full Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title_fullStr Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title_full_unstemmed Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title_short Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda
title_sort prevalence, intensity, and correlates of soil-transmitted helminth infections among school children after a decade of preventive chemotherapy in western rwanda
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767502/
https://www.ncbi.nlm.nih.gov/pubmed/33371488
http://dx.doi.org/10.3390/pathogens9121076
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