Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

We conducted genome-wide association studies (GWAS) of relative intake from the macronutrients fat, protein, carbohydrates, and sugar in over 235,000 individuals of European ancestries. We identified 21 unique, approximately independent lead SNPs. Fourteen lead SNPs are uniquely associated with one...

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Detalles Bibliográficos
Autores principales: Meddens, S. Fleur W., de Vlaming, Ronald, Bowers, Peter, Burik, Casper A. P., Linnér, Richard Karlsson, Lee, Chanwook, Okbay, Aysu, Turley, Patrick, Rietveld, Cornelius A., Fontana, Mark Alan, Ghanbari, Mohsen, Imamura, Fumiaki, McMahon, George, van der Most, Peter J., Voortman, Trudy, Wade, Kaitlin H., Anderson, Emma L., Braun, Kim V. E., Emmett, Pauline M., Esko, Tonũ, Gonzalez, Juan R., Kiefte-de Jong, Jessica C., Langenberg, Claudia, Luan, Jian’an, Muka, Taulant, Ring, Susan, Rivadeneira, Fernando, Snieder, Harold, van Rooij, Frank J. A., Wolffenbuttel, Bruce H. R., Smith, George Davey, Franco, Oscar H., Forouhi, Nita G., Ikram, M. Arfan, Uitterlinden, Andre G., van Vliet-Ostaptchouk, Jana V., Wareham, Nick J., Cesarini, David, Harden, K. Paige, Lee, James J., Benjamin, Daniel J., Chow, Carson C., Koellinger, Philipp D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767645/
https://www.ncbi.nlm.nih.gov/pubmed/32393786
http://dx.doi.org/10.1038/s41380-020-0697-5

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