Cargando…

Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study

OBJECTIVE: To evaluate the efficacy of three surgical approaches for the treatment of cervicothoracic tuberculosis. METHODS: This is a multicenter retrospective study. We analyzed 74 patients with cervicothoracic tuberculosis who were treated in six institutions between January 2000 and January 2015...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Wen‐jie, Tang, Yong, Lyu, Jing‐tong, Yang, Sen, Wang, Dong‐Gui, Zhang, Qiang, Liu, Xun, Deng, Jie‐zhong, Luo, Fei, Hou, Tian‐Yong, Xu, Jian‐zhong, Zhang, Ze‐hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767672/
https://www.ncbi.nlm.nih.gov/pubmed/31568641
http://dx.doi.org/10.1111/os.12527
_version_ 1783629011089358848
author Wu, Wen‐jie
Tang, Yong
Lyu, Jing‐tong
Yang, Sen
Wang, Dong‐Gui
Zhang, Qiang
Liu, Xun
Deng, Jie‐zhong
Luo, Fei
Hou, Tian‐Yong
Xu, Jian‐zhong
Zhang, Ze‐hua
author_facet Wu, Wen‐jie
Tang, Yong
Lyu, Jing‐tong
Yang, Sen
Wang, Dong‐Gui
Zhang, Qiang
Liu, Xun
Deng, Jie‐zhong
Luo, Fei
Hou, Tian‐Yong
Xu, Jian‐zhong
Zhang, Ze‐hua
author_sort Wu, Wen‐jie
collection PubMed
description OBJECTIVE: To evaluate the efficacy of three surgical approaches for the treatment of cervicothoracic tuberculosis. METHODS: This is a multicenter retrospective study. We analyzed 74 patients with cervicothoracic tuberculosis who were treated in six institutions between January 2000 and January 2015. There were 37 male and 37 female patients, with an average age of 24 years (range, 5–62 years). The operative method was selected according to the indications. A total of 33 patients underwent one‐stage anterior surgery (group A); 16 underwent a combined anterior and posterior surgery (group B) and 25 underwent one‐stage posterior surgery (group C). Clinical outcomes, laboratory indexes, and radiological results were analyzed. RESULTS: All cases were followed up for approximately 36–96 months post‐surgery (average, 39 months). At the last follow‐up, patients in all three groups had achieved bone fusion, with pain relief and neurological recovery. No major vessel and nerve injuries were found during the operation. There were significant differences before and after treatment for visual analogue scale (VAS), neck disability index (NDI), and Japanese Orthopedic Association (JOA) score (P < 0.001). Three surgical strategies significantly improved kyphosis (P < 0.001). CONCLUSION: The choice of operation for cervicothoracic tuberculosis should be selected based on the pathological changes, scope, and general physical condition of the patient. The indication for a posterior approach is narrow and it should be used selectively. The combined anterior and posterior approach involved a longer operating time, larger blood loss, and greater trauma, and also required a higher level of surgical skill. Therefore, the indications for this approach should be strictly controlled. Anterior approach surgery for the treatment of cervicothoracic tuberculosis showed excellent efficacy and fewer complications.
format Online
Article
Text
id pubmed-7767672
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley & Sons Australia, Ltd
record_format MEDLINE/PubMed
spelling pubmed-77676722020-12-28 Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study Wu, Wen‐jie Tang, Yong Lyu, Jing‐tong Yang, Sen Wang, Dong‐Gui Zhang, Qiang Liu, Xun Deng, Jie‐zhong Luo, Fei Hou, Tian‐Yong Xu, Jian‐zhong Zhang, Ze‐hua Orthop Surg Clinical Articles OBJECTIVE: To evaluate the efficacy of three surgical approaches for the treatment of cervicothoracic tuberculosis. METHODS: This is a multicenter retrospective study. We analyzed 74 patients with cervicothoracic tuberculosis who were treated in six institutions between January 2000 and January 2015. There were 37 male and 37 female patients, with an average age of 24 years (range, 5–62 years). The operative method was selected according to the indications. A total of 33 patients underwent one‐stage anterior surgery (group A); 16 underwent a combined anterior and posterior surgery (group B) and 25 underwent one‐stage posterior surgery (group C). Clinical outcomes, laboratory indexes, and radiological results were analyzed. RESULTS: All cases were followed up for approximately 36–96 months post‐surgery (average, 39 months). At the last follow‐up, patients in all three groups had achieved bone fusion, with pain relief and neurological recovery. No major vessel and nerve injuries were found during the operation. There were significant differences before and after treatment for visual analogue scale (VAS), neck disability index (NDI), and Japanese Orthopedic Association (JOA) score (P < 0.001). Three surgical strategies significantly improved kyphosis (P < 0.001). CONCLUSION: The choice of operation for cervicothoracic tuberculosis should be selected based on the pathological changes, scope, and general physical condition of the patient. The indication for a posterior approach is narrow and it should be used selectively. The combined anterior and posterior approach involved a longer operating time, larger blood loss, and greater trauma, and also required a higher level of surgical skill. Therefore, the indications for this approach should be strictly controlled. Anterior approach surgery for the treatment of cervicothoracic tuberculosis showed excellent efficacy and fewer complications. John Wiley & Sons Australia, Ltd 2019-09-30 /pmc/articles/PMC7767672/ /pubmed/31568641 http://dx.doi.org/10.1111/os.12527 Text en © 2019 The Authors. Orthopaedic Surgery published by Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Articles
Wu, Wen‐jie
Tang, Yong
Lyu, Jing‐tong
Yang, Sen
Wang, Dong‐Gui
Zhang, Qiang
Liu, Xun
Deng, Jie‐zhong
Luo, Fei
Hou, Tian‐Yong
Xu, Jian‐zhong
Zhang, Ze‐hua
Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title_full Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title_fullStr Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title_full_unstemmed Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title_short Clinical Efficacy of Three Surgical Approaches for the Treatment of Cervicothoracic Tuberculosis: A Multicenter Retrospective Study
title_sort clinical efficacy of three surgical approaches for the treatment of cervicothoracic tuberculosis: a multicenter retrospective study
topic Clinical Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767672/
https://www.ncbi.nlm.nih.gov/pubmed/31568641
http://dx.doi.org/10.1111/os.12527
work_keys_str_mv AT wuwenjie clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT tangyong clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT lyujingtong clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT yangsen clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT wangdonggui clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT zhangqiang clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT liuxun clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT dengjiezhong clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT luofei clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT houtianyong clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT xujianzhong clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy
AT zhangzehua clinicalefficacyofthreesurgicalapproachesforthetreatmentofcervicothoracictuberculosisamulticenterretrospectivestudy