Symmetrical dimethylation of H4R3: A bridge linking DNA damage and repair upon oxidative stress

The DNA lesions caused by oxidative damage are principally repaired by the base excision repair (BER) pathway. 8-oxoguanine DNA glycosylase 1 (OGG1) initiates BER through recognizing and cleaving the oxidatively damaged nucleobase 8-oxo-7,8-dihydroguanine (8-oxoG). How the BER machinery detects and...

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Detalles Bibliográficos
Autores principales: Ma, Zhuang, Wang, Wentao, Wang, Shiwei, Zhao, Xingqi, Ma, Ying, Wu, Congye, Hu, Zhigang, He, Lingfeng, Pan, Feiyan, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Articles from the Special Issue on Redox Signalling and Cardiovascular Disease; Edited by Christopher Kevil and Yabing Chen
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767741/
https://www.ncbi.nlm.nih.gov/pubmed/32739156
http://dx.doi.org/10.1016/j.redox.2020.101653

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