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Nose-to-Brain Delivery by Nanosuspensions-Based in situ Gel for Breviscapine
PURPOSE: Nose-to-brain drug delivery is an effective approach for poorly soluble drugs to bypass the blood–brain barrier. A new drug intranasal delivery system, a nanosuspension-based in situ gel, was developed and evaluated to improve the solubility and bioavailability of the drug and to prolong it...
Autores principales: | Chen, Yingchong, Liu, Yuling, Xie, Jin, Zheng, Qin, Yue, Pengfei, Chen, Liru, Hu, Pengyi, Yang, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767747/ https://www.ncbi.nlm.nih.gov/pubmed/33380794 http://dx.doi.org/10.2147/IJN.S265659 |
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