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METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner

PURPOSE: Hepatocellular carcinoma (HCC) ranks as the fourth leading cause of cancer-related deaths worldwide. N6-methyladenosine (m6A) RNA methylation is the most common modification of messenger RNAs (mRNAs). The prognosis of HCC patients with metastasis remains poor. Our study aimed to elucidate t...

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Detalles Bibliográficos
Autores principales: Shi, Yuntao, Zhuang, Yingying, Zhang, Jialing, Chen, Mengxue, Wu, Shangnong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767748/
https://www.ncbi.nlm.nih.gov/pubmed/33380825
http://dx.doi.org/10.2147/CMAR.S286275